2. Neuronal Signaling
  3. Cholinesterase (ChE) Monoamine Oxidase Amyloid-β
  4. AChE/MAO-IN-1

AChE/MAO-IN-1 (Compound D28) 是一种有效的 AChE、MAO-A 和 MAO-B 抑制剂，对人 AChE、MAO-B 和 MAO-A 的 IC50 分别为 0.0248、0.0409 和 0.1108 μM。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

AChE/MAO-IN-1 Chemical Structure

AChE/MAO-IN-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

AChE/MAO-IN-1 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

查看 Monoamine Oxidase 亚型特异性产品:

查看所有亚型
MAO-A MAO-B

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AChE/MAO-IN-1 (Compound D28) is a potent AChE, MAO-A and MAO-B inhibitor with IC50s of 0.0248, 0.0409 and 0.1108 μM against human AChE, MAO-B and MAO-A, respectively[1].

IC50 & Target[1]

hAChE

0.0248 μM (IC50)

hMAO-B

0.0409 μM (IC50)

hMAO-A

0.1069 μM (Ki)

hMAO-A

0.1108 μM (IC50)

Aβ42

0.1467 μM (IC50)

体外研究
(In Vitro)

AChE/MAO-IN-1 (Compound D28) 具有抗氧化活性，在 DPPH 自由基清除活性测试中的 IC50 为 0.210 ± 0.010 μM[1]。
AChE/MAO-IN-1 抑制 β-淀粉样蛋白 1-42 (Aβ42)，IC50 为 0.1467 ± 0.0053 μM[1]。
AChE/MAO-IN-1 (24 h) 对 NIH/3T3 细胞具有低细胞毒性 (IC50: 6.5162 ± 0.1750 μM)[1]。
AChE/MAO-IN-1 可以高效地结合 MAO-A 的活性位点[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AChE/MAO-IN-1 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: NIH/3T3 mouse fibroblast healthy cell line
Concentration:
Incubation Time: 24 h
Result: Showed cytotoxicity with an IC50 of 6.5162 ± 0.1750 μM.
分子量

378.46

Formula

C23H26N2O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AChE/MAO-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AChE/MAO-IN-1Cholinesterase (ChE)Monoamine OxidaseAmyloid-βMAOβ-amyloid peptideAβAbetaantioxidantAlzheimer’s diseaselow cytotoxicityInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
AChE/MAO-IN-1
目录号：
HY-152109
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z