1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Adipic acid-d4

Adipic acid-d4  (Synonyms: 己二酸-d4;肥酸-d4)

目录号: HY-W017522S2 纯度: ≥98.0%
COA 产品使用指南

Adipic acid-d4 是 Adipic acid 的氘代物。 Adipic acid 被发现与 HMG-CoA 裂解酶缺乏症,肉毒碱激酶缺乏症,中链酰基脱氢酶缺乏症相关,这些都是天生代谢异常导致的。

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Adipic acid-d<sub>4</sub> Chemical Structure

Adipic acid-d4 Chemical Structure

CAS No. : 121311-78-2

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Customer Review

Other Forms of Adipic acid-d4:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Adipic acid-d4 is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

150.17

Formula

C6H6D4O4

CAS 号
性状

固体

颜色

White to off-white

中文名称

己二酸-d4;肥酸-d4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥98.0%

参考文献
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  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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