2. PI3K/Akt/mTOR Apoptosis
  3. Akt Apoptosis
  4. AKT-IN-21

AKT-IN-21 (compound C36) 是有效的 AKT 抑制剂，具有广谱细胞毒性和抗癌活性。AKT-IN-21 还通过下调 PI3K/AKT 通路来阻止细胞周期，诱导癌细胞凋亡 (apoptosis)。

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AKT-IN-21 Chemical Structure

AKT-IN-21 Chemical Structure

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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AKT-IN-21 相关抗体

Top Publications Citing Use of Products

查看 Akt 亚型特异性产品:

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Akt Akt1 Akt2 Akt3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AKT-IN-21 (compound C36) is a potent AKT inhibitor with broad-spectrum cytotoxicity and anticancer activity. AKT-IN-21 also blocks the cell cycle and induces apoptosis of cancer cells by down-regulating the PI3K/AKT pathway[1].

体外研究
(In Vitro)

AKT-IN-21 在多种癌细胞中显示出抗增殖抑制活性和细胞毒性，IC50 分别为 2.33 μM (LNCaP)、2.38 μM (K562)、1.98 μM (HepG2)、3.95 μM (LX-2)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AKT-IN-21 相关抗体:
分子量

438.56

Formula

C26H34N2O4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AKT-IN-21 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AKT-IN-21AktApoptosisPKBProtein kinase BantitumorCytotoxicityPI3K/AKT pathwayPrenylated chalcone derivativesInhibitorinhibitorinhibit

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产品名称：
AKT-IN-21
目录号：
HY-161144
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