1. PI3K/Akt/mTOR
  2. Akt PI3K
  3. AM-9635

AM-9635 是一种选择性 PI3Kδ 抑制剂,具有口服生物利用度,以及良好的体内外活性和药效学特性。AM-9635 抑制 PI3Kδ 依赖的 B 细胞受体介导的 AKT 磷酸化,并且抑制海兔血蓝蛋白 (KLH) 免疫的大鼠产生特异性特异性 IgGIgM 抗体。

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AM-9635 Chemical Structure

AM-9635 Chemical Structure

CAS No. : 1338483-10-5

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     可免费申领三个不同产品的试用装。

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规格 是否有货
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AM-9635 is a selective PI3Kδ inhibitor with oral bioavailability, good in vitro and in vivo activity and pharmacodynamic properties. AM-9635 inhibits PI3Kδ-dependent B cell receptor-mediated AKT phosphorylation and suppresses the production of specific IgG and IgM antibodies in rats immunized with Aplysia leocyanin (KLH).

分子量

392.36

Formula

C19H14F2N8

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
AM-9635
目录号:
HY-118374
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