2. Immunology/Inflammation
  3. Interleukin Related
  4. Raleukin

Raleukin  (Synonyms: 阿那白滞素; AMG-719; Anakinra)

目录号: HY-108841 纯度: ≥99.4%
COA

摩尔计算器

Raleukin (AMG-719) 是重组的、非溶酶化的 白细胞介素-1受体 (IL-1R) 的拮抗剂。Raleukin (AMG-719) 是第一个用于阻断促炎作用的生物制剂。

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Raleukin Chemical Structure

Raleukin Chemical Structure

CAS No. : 143090-92-0

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规格 价格 是否有货 数量
1 mg ￥1591
In-stock
5 mg ￥3500
In-stock
10 mg ￥5500
In-stock
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100 mg   询价  

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Customer Review

Raleukin 相关抗体

Top Publications Citing Use of Products

查看 Interleukin Related 亚型特异性产品:

查看所有亚型
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Raleukin (AMG-719) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin (AMG-719) is the first biological agent to block the pro-inflammatory effects[1][2].

IC50 & Target

IL-1

 

体内研究
(In Vivo)

Combined Etanercept (5 mg/kg, ip) and Anakinra (100 mg/kg, ip. daily for 7 days) substantially improves marginal mass human islet engraftment in immunodeficient mice[2].
Raleukin (AMG-719) enhances tumor growth inhibition in mice receiving peptide vaccination and β-(1-3),(1-6)-D-glucan[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

17257.60

Formula

C759H1186N208O232S10
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

阿那白滞素
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: ≥99.4%

COA (265 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Raleukin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Raleukin143090-92-0AMG-719 Anakinra阿那白滞素AMG719AMG 719Interleukin RelatedILrheumatoidarthritisInhibitorinhibitorinhibit

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