2. Apoptosis Autophagy JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. Apoptosis Autophagy EGFR
  4. Anticancer agent 133

Anticancer agent 133 (compound Rh2) 是一种具有细胞毒性和抗转移活性的抗癌剂。Anticancer agent 133 诱导细胞周期阻滞、细胞凋亡 (apoptosis) 和自噬 (autophagy)。Anticancer agent 133 还通过抑制 FAK 调节的整合素 β1 介导的 EGFR 表达来抑制细胞转移。

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Anticancer agent 133 Chemical Structure

Anticancer agent 133 Chemical Structure

CAS No. : 2758905-51-8

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Anticancer agent 133 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Anticancer agent 133 (compound Rh2) is an anti-cancer agent with cytotoxic and antimetastatic activities. Anticancer agent 133 induces cell cycle arrest, apoptosis, and autophagy. Anticancer agent 133 also inhibits cell metastasis via suppression of EGFR expression mediated by FAK-regulated integrin β1[1].

分子量

602.71

Formula

C24H19Cl3N5ORh
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anticancer agent 133 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 1332758905-51-8Anticancer agent133Anticancer agent-133ApoptosisAutophagyEGFREpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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