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Antitumor agent-119 

目录号: HY-156775 纯度: 98.03%
COA 产品使用指南

摩尔计算器

Antitumor agent-119（化合物13K）是一种具有抗癌活性的 2-苯并恶唑基腙衍生物。Antitumor agent-119 抑制 Butkitt、CCRF-CEM、HeLa 和 HT-29 的细胞生长，IC50 值分别为 30 nM、140 nM、100 nM 和 40 nM。

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Antitumor agent-119 Chemical Structure

Antitumor agent-119 Chemical Structure

CAS No. : 913169-79-6

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规格 价格 是否有货 数量
1 mg ￥1200
In-stock
5 mg ￥3800
In-stock
10 mg ￥5890
In-stock
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Antitumor agent-119 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antitumor agent-119 (compound 13K) is a 2-benzoxazolyl hydrazone derivative with anticancer activities. Antitumor agent-119 inhibits the cell growth of Butkitt, CCRF-CEM, HeLa, and HT-29 with IC50 values of 30 nM, 140 nM, 100 nM, and 40 nM, respectively[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Burkitts lymphoma cell IC50
0.03 μM
Compound: E-13k, NSC-693638
Antiproliferative activity against Burkitt cells by MTT assay
Antiproliferative activity against Burkitt cells by MTT assay
[PMID: 17034140]
CCRF-CEM IC50
0.14 μM
Compound: E-13k, NSC-693638
Antiproliferative activity against CCRF-CEM cells by MTT assay
Antiproliferative activity against CCRF-CEM cells by MTT assay
[PMID: 17034140]
HeLa IC50
0.1 μM
Compound: E-13k, NSC-693638
Antiproliferative activity against HeLa cells by SRB assay
Antiproliferative activity against HeLa cells by SRB assay
[PMID: 17034140]
HT-29 IC50
0.04 μM
Compound: E-13k, NSC-693638
Antiproliferative activity against HT29 cells by SRB assay
Antiproliferative activity against HT29 cells by SRB assay
[PMID: 17034140]
分子量

302.33

Formula

C18H14N4O
CAS 号
性状

固体

颜色

Off-white to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: 98.03%

COA (286 KB) HNMR (128 KB) RP-HPLC (161 KB) LCMS (197 KB)

产品使用指南 (1538 KB)
参考文献

Antitumor agent-119 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-119913169-79-6Antitumor agent119Antitumor agent 119OthersAntitumor agent2-benzoxazolyl hydrazone derivativeInhibitorinhibitorinhibit

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