1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. ATP magnesium

ATP magnesium  (Synonyms: Adenosine 5'-triphosphate magnesium)

目录号: HY-B2176E
产品使用指南

ATP (Adenosine 5'-triphosphate) magnesium 是体内能量储存和代谢的重要物质,为代谢提供能量,同时在细胞中作为辅酶发挥作用。ATP magnesium 是免疫和炎症中重要的内源性信号分子。

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ATP magnesium Chemical Structure

ATP magnesium Chemical Structure

CAS No. : 1476-84-2

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MCE 顾客使用本产品发表的 69 篇科研文献

WB

    ATP magnesium purchased from MCE. Usage Cited in: Transl Res. 2022.

    LPS/ATP treatment significantly promotes expression of NLRP3 and production of N-GSDMD in HAEC. HAEC are pretreated with LPS (500ng/ml) for 5 h and then stimulated with ATP (5 mM) for 1 h.
    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    ATP (Adenosine 5'-triphosphate) magnesium is a central component of energy storage and metabolism in vivo. ATP magnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP magnesium is an important endogenous signaling molecule in immunity and inflammation[1][2].

    体外研究
    (In Vitro)

    ATP (5 mM;1 小时) 与 LPS (1 μg/mL) 共同处理对 HGFs 中 NLRP3 炎性体的激活具有协同作用[3]
    ATP (2 mM;0.5-24 小时) 以 caspase-1 激活依赖性方式诱导 BMDM 分泌 IL-1β、KC 和 MIP-2[4]
    ATP 促进中性粒细胞趋化性体外[4]

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

    体内研究
    (In Vivo)

    ATP (50 mg/kg;ip) magnesium 在体内保护小鼠免受细菌感染[4]
    ATP magnesium 在体内诱导 IL-1β、KC 和 MIP-2 的分泌以及中性粒细胞募集[4]

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

    分子量

    531.49

    Formula

    C10H16MgN5O13P3

    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.

    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.

    纯度 & 产品资料
    参考文献
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    • 稀释计算器

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    目录号:
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