2. Epigenetics Vitamin D Related/Nuclear Receptor
  3. Histone Acetyltransferase Estrogen Receptor/ERR
  4. BAY-184

BAY-184 是一种选择性的口服 KAT6A 和 KAT6B 抑制剂。BAY-184 抑制 KAT6A/KAT6B 活性，IC50 分别为 71 nM 和 83 nM。BAY-184 抑制 ERα<、b> 转录活性。BAY-184 抑制多种乳腺癌亚型的细胞增殖，并抑制肿瘤生长。

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BAY-184 Chemical Structure

BAY-184 Chemical Structure

CAS No. : 2520347-03-7

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规格 是否有货
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BAY-184 相关抗体

Top Publications Citing Use of Products

查看 Histone Acetyltransferase 亚型特异性产品:

查看所有亚型
CBP/p300 GCN5/PCAF TIP60 MOZ/MORF HBO1

查看 Estrogen Receptor/ERR 亚型特异性产品:

查看所有亚型
Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BAY-184 is a selective and orally active KAT6A and KAT6B inhibitor. BAY-184 inhibits KAT6A/KAT6B activity with an IC50 of 71 nM and 83 nM. respectively BAY-184 inhibits ERα transcriptional activity. BAY-184 inhibits proliferation of diverse breast cancer subtypes, and inhibits tumor growth[1].

分子量

420.48

Formula

C23H20N2O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BAY-184 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BAY-1842520347-03-7BAY184BAY 184Histone AcetyltransferaseEstrogen Receptor/ERRHATsHATInhibitorinhibitorinhibit

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产品名称：
BAY-184
目录号：
HY-159957
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