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  4. Betulin diacetate

Betulin diacetate  (Synonyms: Betulin 3,28-diacetate)

目录号: HY-N9437 纯度: ≥95.0%
COA 产品使用指南

摩尔计算器

Betulin diacetate 是一个三萜类化合物和 Betulin 衍生物，具有抗 AID 和抗癌活性。

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Betulin diacetate Chemical Structure

Betulin diacetate Chemical Structure

CAS No. : 1721-69-3

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规格 价格 是否有货 数量
5 mg ￥312
In-stock
10 mg ￥500
In-stock
25 mg ￥900
In-stock
50 mg ￥1400
In-stock
100 mg ￥2100
In-stock
200 mg   询价  
500 mg   询价  

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Betulin diacetate 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Betulin diacetate, a triterpene and derivative of Betulin, is an anti-AID agent and also possesses anti-cancer activity[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
518A2 EC50
> 30 μM
Compound: 1
Cytotoxicity against human 518A2 cells after 96 hrs by SRB assay
Cytotoxicity against human 518A2 cells after 96 hrs by SRB assay
[PMID: 27142753]
518A2 EC50
> 30 μM
Compound: 29
Cytotoxicity against human 518A2 cells after 96 hrs by SRB assay
Cytotoxicity against human 518A2 cells after 96 hrs by SRB assay
[PMID: 26547057]
A2780 EC50
> 30 μM
Compound: 29
Cytotoxicity against human A2780 cells assessed as reduction in cell viability incubated for 96 hrs by SRB assay
Cytotoxicity against human A2780 cells assessed as reduction in cell viability incubated for 96 hrs by SRB assay
[PMID: 31718946]
A2780 EC50
> 30 μM
Compound: 29
Cytotoxicity against human A2780 cells after 96 hrs by SRB assay
Cytotoxicity against human A2780 cells after 96 hrs by SRB assay
[PMID: 26547057]
A2780 EC50
20.3 μM
Compound: 1
Cytotoxicity against human A2780 cells after 96 hrs by SRB assay
Cytotoxicity against human A2780 cells after 96 hrs by SRB assay
[PMID: 27142753]
A-375 EC50
> 30 μM
Compound: 29
Cytotoxicity against human A375 cells assessed as reduction in cell viability incubated for 96 hrs by SRB assay
Cytotoxicity against human A375 cells assessed as reduction in cell viability incubated for 96 hrs by SRB assay
[PMID: 31718946]
A549 EC50
> 30 μM
Compound: 29
Cytotoxicity against human A549 cells after 96 hrs by SRB assay
Cytotoxicity against human A549 cells after 96 hrs by SRB assay
[PMID: 26547057]
A549 EC50
21.5 μM
Compound: 1
Cytotoxicity against human A549 cells after 96 hrs by SRB assay
Cytotoxicity against human A549 cells after 96 hrs by SRB assay
[PMID: 27142753]
B16 ED50
3.4 μM
Compound: 8
Induction of melanogenesis in mouse B16 2F2 cells assessed as intracellular melanin content after 3 days
Induction of melanogenesis in mouse B16 2F2 cells assessed as intracellular melanin content after 3 days
[PMID: 12027734]
B16 IC50
36.8 μM
Compound: 8
Growth inhibition of mouse B16 2F2 cells after 3 days
Growth inhibition of mouse B16 2F2 cells after 3 days
[PMID: 12027734]
BXPC-3 GI50
> 10 μg/mL
Compound: 5
Cytotoxicity against human BxPC3 cells after 48 hrs by SRB assay
Cytotoxicity against human BxPC3 cells after 48 hrs by SRB assay
[PMID: 24694263]
DU-145 GI50
> 10 μg/mL
Compound: 5
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
[PMID: 24694263]
FaDu EC50
> 30 μM
Compound: 29
Cytotoxicity against human FADU cells assessed as reduction in cell viability incubated for 96 hrs by SRB assay
Cytotoxicity against human FADU cells assessed as reduction in cell viability incubated for 96 hrs by SRB assay
[PMID: 31718946]
H9 EC50
> 189.8 μM
Compound: 24
Anti-HIV activity against acutely infected H9 lymphocytes. Activity expressed as concentration of compound able to suppress HIV replication by 50%.
Anti-HIV activity against acutely infected H9 lymphocytes. Activity expressed as concentration of compound able to suppress HIV replication by 50%.
[PMID: 9804704]
HeLa EC50
> 30 μM
Compound: 1
Cytotoxicity against human HeLa cells after 96 hrs by SRB assay
Cytotoxicity against human HeLa cells after 96 hrs by SRB assay
[PMID: 27142753]
HT-29 EC50
> 30 μM
Compound: 29
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability incubated for 96 hrs by SRB assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability incubated for 96 hrs by SRB assay
[PMID: 31718946]
HT-29 EC50
25.7 μM
Compound: 1
Cytotoxicity against human HT-29 cells after 96 hrs by SRB assay
Cytotoxicity against human HT-29 cells after 96 hrs by SRB assay
[PMID: 27142753]
KM-20L2 GI50
> 10 μg/mL
Compound: 5
Cytotoxicity against human KM20L2 cells after 48 hrs by SRB assay
Cytotoxicity against human KM20L2 cells after 48 hrs by SRB assay
[PMID: 24694263]
MCF7 GI50
> 10 μg/mL
Compound: 5
Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
[PMID: 24694263]
MCF7 EC50
> 30 μM
Compound: 29
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 96 hrs by SRB assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 96 hrs by SRB assay
[PMID: 31718946]
MCF7 EC50
> 30 μM
Compound: 1
Cytotoxicity against human MCF7 cells after 96 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 96 hrs by SRB assay
[PMID: 27142753]
MCF7 EC50
> 30 μM
Compound: 29
Cytotoxicity against human MCF7 cells after 96 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 96 hrs by SRB assay
[PMID: 26547057]
NCI-H460 GI50
> 10 μg/mL
Compound: 5
Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
[PMID: 24694263]
NIH3T3 EC50
> 30 μM
Compound: 29
Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability incubated for 96 hrs by SRB assay
Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability incubated for 96 hrs by SRB assay
[PMID: 31718946]
NIH3T3 EC50
> 30 μM
Compound: 29
Cytotoxicity against mouse NIH/3T3 cells after 96 hrs by SRB assay
Cytotoxicity against mouse NIH/3T3 cells after 96 hrs by SRB assay
[PMID: 26547057]
P388 ED50
0.806 μg/mL
Compound: 5
Cytotoxicity against mouse P388 cells after 48 hrs
Cytotoxicity against mouse P388 cells after 48 hrs
[PMID: 24694263]
SF-268 GI50
> 10 μg/mL
Compound: 5
Cytotoxicity against human SF268 cells after 48 hrs by SRB assay
Cytotoxicity against human SF268 cells after 48 hrs by SRB assay
[PMID: 24694263]
分子量

526.79

Formula

C34H54O4
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
细胞实验： 

Ethanol 中的溶解度 : 5 mg/mL (9.49 mM; 超声助溶)

DMSO 中的溶解度 : < 1 mg/mL (insoluble or slightly soluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.8983 mL 9.4914 mL 18.9829 mL
5 mM 0.3797 mL 1.8983 mL 3.7966 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Betulin diacetate 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 1.8983 mL 9.4914 mL 18.9829 mL 47.4572 mL
5 mM 0.3797 mL 1.8983 mL 3.7966 mL 9.4914 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Betulin diacetate1721-69-3Betulin 3,28-diacetateHIVHuman immunodeficiency virusInhibitorinhibitorinhibit

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目录号：
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