2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. Broussonin A

Broussonin A 是一种有效的 BChE 抑制剂，IC50 为 4.16 µM。 Broussonin A 是一种二芳基丙烷天然产物，可以从 Broussonetia papyrifera 的树皮中固体发酵后分离出来。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Broussonin A Chemical Structure

Broussonin A Chemical Structure

CAS No. : 73731-87-0

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Broussonin A 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Broussonin A is a potent BChE inhibitor, with an IC50 of 4.16 µM. Broussonin A is a diarylpropane natural product that can be isolated from the bark of Broussonetia papyrifera after solid fermentation[1][2][3].

IC50 & Target

BChE

4.16 μM (IC50)

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
3T3-L1 IC50
74.5 μM
Compound: 8
Antiadipogenic activity against mouse 3T3L1 cells assessed as inhibition of differentiation after 7 days by oil-red O staining
Antiadipogenic activity against mouse 3T3L1 cells assessed as inhibition of differentiation after 7 days by oil-red O staining
[PMID: 19757853]
CV-1 EC50
0.53 μM
Compound: 1
Transactivation of human recombinant ERbeta expressed in african green monkey CV1 cells co-expressing ERE-Luc after 24 hrs by luciferase reporter gene assay
Transactivation of human recombinant ERbeta expressed in african green monkey CV1 cells co-expressing ERE-Luc after 24 hrs by luciferase reporter gene assay
[PMID: 20493686]
CV-1 EC50
1.59 μM
Compound: 1
Transactivation of human recombinant ERalpha expressed in african green monkey CV1 cells co-expressing ERE-Luc after 24 hrs by luciferase reporter gene assay
Transactivation of human recombinant ERalpha expressed in african green monkey CV1 cells co-expressing ERE-Luc after 24 hrs by luciferase reporter gene assay
[PMID: 20493686]
体外研究
(In Vitro)

Broussonin A（0.1-10 µM，30 分钟）通过调节细胞周期相关蛋白的表达和视网膜母细胞瘤蛋白的磷酸化状态来抑制 VEGF-A 刺激的内皮细胞增殖[1]。
Broussonin A（0-10 µM，30 分钟）消除 VEGF-A 刺激的血管生成反应，包括大鼠主动脉环的内皮细胞迁移、侵袭、管形成和微血管形成[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Broussonin A 相关抗体:
分子量

258.31

Formula

C16H18O3
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Broussonin A 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Broussonin A73731-87-0Cholinesterase (ChE)ButyrylcholinesteraseBroussonetia papyriferaanti-angiogenicHuman umbilical vein endothelial cellsHUVECsInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Broussonin A
目录号：
HY-N2960
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z