1. Apoptosis PI3K/Akt/mTOR Cell Cycle/DNA Damage
  2. Apoptosis PI3K DNA/RNA Synthesis
  3. C-8 Ceramide-1-phosphate

C-8 Ceramide-1-phosphate  (Synonyms: C-8-神经酰胺-1-磷酸)

目录号: HY-165099
产品使用指南

C-8 Ceramide-1-phosphate 是一种细胞凋亡 (apoptosis) 抑制剂和细胞存活诱导剂,可以刺激 DNA 合成 (DNA synthesis) 和细胞分裂。C-8 Ceramide-1-phosphate 能够抑制酸性鞘磷脂酶 (SMase) 并刺激 PI3-K,进而产生 PIP3,PIP3 也能抑制酸性 SMase。C-8 Ceramide-1-phosphate 和神经酰胺可以通过激酶和磷酸酶活性在细胞内相互转化,两者的平衡对细胞和组织稳态至关重要。

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C-8 Ceramide-1-phosphate Chemical Structure

C-8 Ceramide-1-phosphate Chemical Structure

CAS No. : 158983-53-0

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  • 生物活性

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生物活性

C-8 Ceramide-1-phosphate is a cell apoptosis inhibitor and a cell survival inducer that can stimulate DNA synthesis and cell division. C-8 Ceramide-1-phosphate can inhibit acidic sphingomyelinase (SMase) and stimulate PI3-K, which in turn produces PIP3; PIP3 can also inhibit acidic SMase. The C-8 Ceramide-1-phosphate and ceramide can be interconverted in cells through kinase and phosphatase activity, and maintaining the balance between the two is crucial for cellular and tissue homeostasis[1][2].

分子量

505.67

Formula

C26H52NO6P

CAS 号
中文名称

C-8-神经酰胺-1-磷酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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C-8 Ceramide-1-phosphate
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