1. Apoptosis Stem Cell/Wnt Cell Cycle/DNA Damage
  2. c-Myc Casein Kinase
  3. c-Myc inhibitor 7

c-Myc inhibitor 7 是 c-Myc 抑制剂以及多靶点蛋白质降解剂。c-Myc inhibitor 7 可有效降解多种肿瘤细胞中的 c-MycCK1αGSPT1IKZF1/2/3 蛋白。c-Myc inhibitor 7 可用于 c-Myc 高表达相关疾病的研究,如癌症、心脑血管疾病和病毒感染。

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c-Myc inhibitor 7 Chemical Structure

c-Myc inhibitor 7 Chemical Structure

CAS No. : 2883535-99-5

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查看 Casein Kinase 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

c-Myc inhibitor 7 is a c-Myc inhibitor and a multiple target protein degrader. c-Myc inhibitor 7 effective degrades c-MYC, CK1α, GSPT1 and IKZF1/2/3 proteins in a variety of tumor cells. c-Myc inhibitor 7 can be used for c-Myc high expression related disease research, such as cancer, cardiovascular and cerebrovascular diseases, and viral infection[1].

体外研究
(In Vitro)

c-Myc inhibitor 7 (0-10 mM;3 天) 抑制 HL60 细胞增殖,IC50 值为 0.5 nM[1]
c-Myc inhibitor 7 促进 60-90% HL60 细胞中蛋白的降解[1]
c-Myc inhibitor 7 (1,3,10 和 100 nM;24 小时) 在多种细胞系中降解 c-Myc,CKla,GSPTl,IKZFl,IKZF2 和 IKZF3 蛋白[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

614.65

Formula

C35H30N6O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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c-Myc inhibitor 7
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HY-148837
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