1. GPCR/G Protein Neuronal Signaling
  2. 5-HT Receptor
  3. Capeserod

Capeserod  (Synonyms: SL65.0155 free base)

目录号: HY-160921 纯度: 98.66%
COA 产品使用指南

Capeserod (SL65.0155 free base) 是血清素受体 (5-HT receptor) 激动剂,对 5-HT4 receptor 的 Ki 为 0.6 nM。Capeserod 增强海马体中磷酸化 cAMP 反应元件结合蛋白 (p-CREB)、血管内皮生长因子 (VEGF)、脑源性神经营养因子 (BDNF) 和 B 细胞淋巴瘤-2蛋白 (Bcl-2) 的表达,并在 Wistar 大鼠模型中表现出抗抑郁活性。

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Capeserod Chemical Structure

Capeserod Chemical Structure

CAS No. : 769901-96-4

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
1 mg ¥2100
In-stock
5 mg ¥5250
In-stock
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100 mg   询价  

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Customer Review

Other Forms of Capeserod:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Capeserod (SL65.0155 free base) is an agonist for serotonin receptor (5-HT receptor), with a Ki of 0.6 nM for 5-HT4 receptor. Capeserod enhances expression of phopshorilated cAMP-response element binding protein (p-CREB), vascular endothelium growth factor (VEGF), brain-derived neurotrophic factor (BDNF) and B cell lymphoma-2 (Bcl-2) proteins in hippocampus, and exhibits antidepressant-like efficacy in Wistar rats models[1].

IC50 & Target

5-HT4 Receptor

0.6 nM (Ki)

分子量

456.92

Formula

C23H25ClN4O4

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Capeserod
目录号:
HY-160921
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