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  5. Catechin 7-O-β-D-glucopyranoside

Catechin 7-O-β-D-glucopyranoside 

目录号: HY-N10587 纯度: 99.48%
COA 产品使用指南 技术支持

Catechin 7-O-beta-D-glucopyranoside 是一种具有口服活性天然产物,发现于 Ulmus davidiana 和 Paeonia obovata。Catechin 7-O-beta-D-glucopyranoside 具有抗氧化和抗炎活性,并可减轻线粒体功能障碍,可用于肠道炎症性疾病的研究。

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Catechin 7-O-β-D-glucopyranoside Chemical Structure

Catechin 7-O-β-D-glucopyranoside Chemical Structure

CAS No. : 65597-47-9

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1 mg ¥480
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5 mg ¥1180
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10 mg ¥1900
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Catechin 7-O-beta-D-glucopyranoside is an orally active natural product found in Ulmus davidiana and Paeonia obovata. Catechin 7-O-β-D-glucopyranoside shows antioxidant and anti-inflammatory activities, and attenuates mitochondrial dysfunction. Catechin 7-O-beta-D-glucopyranoside can be used in intestinal inflammatory disease research[1][2][3].

体外研究
(In Vitro)

Catechin 7-O-β-D-glucopyranoside (10 μg/mL; 24 h) shows protective effect against Streptozotocin-induced cell damage by its antioxidant effects and the attenuation of mitochondrial dysfunction[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[3]

Cell Line: RINm5F rat pancreatic β-cells
Concentration: 10 μg/mL
Incubation Time: 24 hours
Result: Increased the MnSOD level attenuated by Streptozotocin treatment.
Restored the Streptozotocin-induced reduction in mitochondrial CAT level.
体内研究
(In Vivo)

Catechin 7-O-β-D-glucopyranoside (intraperitoneal injection; 10 mg/kg; once) treatment shows mild protective effect against lethality induced by LPS/D-GalN[1].
Catechin 7-O-β-D-glucopyranoside (oral administration; 10 mg/kg; once daily; 7 d) treatment prevents intestinal inflammatory damages in TNBS model of rat colitis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice injected with LPS/D-GalN[1]
Dosage: 10 mg/kg
Administration: Intraperitoneal injection; 10 mg/kg; once
Result: Showed 80% LPS/DGalN-induced lethality in mice.
Animal Model: Rat model of trinitrobenzenesulfonic acid (TNBS)-induced colitis [2]
Dosage: 10 mg/kg
Administration: Oral administration; 10 mg/kg; once daily; 7 days
Result: Suppressed body weight loss and intestinal inflammatory damages in TNBS-induced colitic rats.
Reduced myeloperoxidase activity and malondialdehyde level, but increased glutathione level in the TNBS colitic rats.
分子量

452.41

Formula

C21H24O11

CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
细胞实验: 

DMSO 中的溶解度 : 125 mg/mL (276.30 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.2104 mL 11.0519 mL 22.1038 mL
5 mM 0.4421 mL 2.2104 mL 4.4208 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2104 mL 11.0519 mL 22.1038 mL 55.2596 mL
5 mM 0.4421 mL 2.2104 mL 4.4208 mL 11.0519 mL
10 mM 0.2210 mL 1.1052 mL 2.2104 mL 5.5260 mL
15 mM 0.1474 mL 0.7368 mL 1.4736 mL 3.6840 mL
20 mM 0.1105 mL 0.5526 mL 1.1052 mL 2.7630 mL
25 mM 0.0884 mL 0.4421 mL 0.8842 mL 2.2104 mL
30 mM 0.0737 mL 0.3684 mL 0.7368 mL 1.8420 mL
40 mM 0.0553 mL 0.2763 mL 0.5526 mL 1.3815 mL
50 mM 0.0442 mL 0.2210 mL 0.4421 mL 1.1052 mL
60 mM 0.0368 mL 0.1842 mL 0.3684 mL 0.9210 mL
80 mM 0.0276 mL 0.1381 mL 0.2763 mL 0.6907 mL
100 mM 0.0221 mL 0.1105 mL 0.2210 mL 0.5526 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Catechin 7-O-β-D-glucopyranoside
目录号:
HY-N10587
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