2. Others Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Glutathione Reductase
  4. Dantrolene-13C3

Dantrolene-13C3  (Synonyms: F 368-13C3)

目录号: HY-12542S 纯度: ≥99.0%
COA 产品使用指南

摩尔计算器

Dantrolene-13C3 是 13C3 标记的 Dantrolene。Dantrolene (F368) 是一种肌肉松弛剂，非竞争性地抑制人红细胞谷胱甘肽还原酶 (glutathione reductase)，Ki 和 IC50 值分别为 111.6 μM 和 52.3 μM。 Dantrolene 是一种兰尼碱受体拮抗剂和 Ca2+ 信号稳定剂。Dantrolene 可用于肌肉痉挛、恶性高热

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Dantrolene-<sup>13</sup>C<sub>3</sub> Chemical Structure

Dantrolene-13C3 Chemical Structure

CAS No. : 1185234-99-4

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Other Forms of Dantrolene-13C3:

Dantrolene-13C3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dantrolene-13C3 is the 13C3 labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Dantrolene-13C3 相关抗体:
分子量

317.23

Formula

C1113C3H10N4O5
CAS 号
非标记 CAS

24868-20-0
性状

固体

颜色

Off-white to light yellow

中文名称

丹曲洛林-13C3；丹曲林钠-13C3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Dantrolene-13C3 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dantrolene-13C31185234-99-4F 368-13C3丹曲洛林-13C3丹曲林钠-13C3Isotope-Labeled CompoundsGlutathione ReductaseInhibitorinhibitorinhibit

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目录号：
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