2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. DB-959

DB-959  (Synonyms: PPARδ/γ agonist 1)

目录号: HY-124244
产品使用指南

摩尔计算器

DB-959 (PPARδ/γ agonist 1) 是一种有效 PPAR 激动剂，靶向 PPAR δ/γ。DB-959 可改善 Streptozotocin (HY-13753) 诱导的小鼠的空间学习和记忆能力，有潜力改善阿尔茨海默症 (AD)。

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DB-959 Chemical Structure

DB-959 Chemical Structure

CAS No. : 1257641-15-8

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规格 是否有货
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DB-959 的其他形式现货产品:

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DB-959 相关抗体

Top Publications Citing Use of Products

查看 PPAR 亚型特异性产品:

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PPARα PPARβ/δ PPARγ PPAR PPARδ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DB-959 (PPARδ/γ agonist 1) is a potent PPAR agonist targeting PPARδ/γ. DB-959 improves spatial learning and memory in mice induced by Streptozotocin (HY-13753) and has the potential to improve Alzheimer's disease (AD).[1].

体内研究
(In Vivo)

PPARδ/γ agonist 1 (1 mg/kg；灌胃；每日，连续 16 天) 可恢复 Streptozotocin 诱导的 Long Evans 大鼠的运动功能障碍[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: STZ-mediated Long Evans rats[1]
Dosage: 1 mg/kg
Administration: Oral gavage; daily, for 16 days
Result: Improved performance in the STZ-mediated rats and had neuroprotective for both granule and Purkinje cells.
分子量

421.49

Formula

C25H27NO5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DB-959 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DB-9591257641-15-8PPARδ/γ agonist 1DB959DB 959PPARPeroxisome proliferator-activated receptorsneuroprotectivegranule cellsPurkinje cellsAlzheimer’s diseaseInhibitorinhibitorinhibit

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