2. Anti-infection Metabolic Enzyme/Protease
  3. Fungal Phosphodiesterase (PDE)
  4. Deacetylsclerotiorin

Deacetylsclerotiorin 是一种可以从真菌 Bartalinia robillardoides 菌株 LF550 中分离得到的氯氮唑啉类的次生代谢物。Deacetylsclerotiorin 对白色念珠菌 (IC50=24 μM)，红毛癣菌 (IC50=2.83 μM) 和小麦壳针孢 (IC50=7..45 μM) 有明显的抑制作用。此外，Deacetylsclerotiorin 还表现出对酶磷酸二酯酶 4 (PDE4) 的抑制作用 (IC50=2.8 μM)。

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Deacetylsclerotiorin Chemical Structure

Deacetylsclerotiorin Chemical Structure

CAS No. : 34696-50-9

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Deacetylsclerotiorin 相关抗体

Top Publications Citing Use of Products

查看 Phosphodiesterase (PDE) 亚型特异性产品:

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PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

  • 生物活性

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生物活性

Deacetylsclerotiorin is a secondary metabolite of chloramphenicol isolated from the fungus Bartalinia robillardoides strain LF550. Deacetylsclerotiorin has significant inhibitory effects on Candida albicans (IC50=24 μM), Trichophyton rubrum (IC50=2.83 μM) and Septoria tritici (IC50=7..45 μM). In addition, Deacetylsclerotiorin also exhibits inhibitory effects on the enzyme phosphodiesterase 4 (PDE4) (IC50=2.8 μM)[1].

IC50 & Target[1]

PDE4

2.8 μM (IC50)

分子量

348.82

Formula

C19H21ClO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Deacetylsclerotiorin 相关分类

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Keywords:

Deacetylsclerotiorin34696-50-9FungalPhosphodiesterase (PDE)Secondary metabolitesAntimicrobial activityPDE4Inhibitorinhibitorinhibit

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