2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. Dibenzyl trisulfide

Dibenzyl trisulfide  (Synonyms: DTS)

目录号: HY-129461
产品使用指南

摩尔计算器

Dibenzyl trisulfide (DTS) 是 Petiveria alliacea L. 分离得到的一种活性成分。Dibenzyl trisulfide 抑制细胞增殖和迁移。Dibenzyl trisulfide 降低了 BAK-1 和 LTA 的 mRNA 和蛋白质表达。Dibenzyl trisulfide 诱导溶酶体膜通透性和组织蛋白酶 B 释放。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Dibenzyl trisulfide Chemical Structure

Dibenzyl trisulfide Chemical Structure

CAS No. : 6493-73-8

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Dibenzyl trisulfide 相关抗体

Top Publications Citing Use of Products

查看 Cathepsin 亚型特异性产品:

查看所有亚型
Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dibenzyl trisulfide (DTS) is an active ingredient that can be isolated from Petiveria alliacea L.. Dibenzyl trisulfide inhibits cell proliferation and migration. Dibenzyl trisulfide decreased the mRNA and protein expression of BAK-1 and LTA. Dibenzyl trisulfide induces lysosomal membrane permeabilization and cathepsin B release[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A2780 IC50
0.4 μM
Compound: 4
Antitumor activity against human A2780 cell line by RTCES assay
Antitumor activity against human A2780 cell line by RTCES assay
[PMID: 16828553]
HeLa IC50
2.5 μM
Compound: 4
Antitumor activity against human HeLa cell line by RTCES assay
Antitumor activity against human HeLa cell line by RTCES assay
[PMID: 16828553]
HepG2 IC50
> 100 μM
Compound: 4
Antitumor activity against human HepG2 cell line by RTCES assay
Antitumor activity against human HepG2 cell line by RTCES assay
[PMID: 16828553]
HT-1080 IC50
1.9 μM
Compound: 4
Antitumor activity against human HT1080 cell line by RTCES assay
Antitumor activity against human HT1080 cell line by RTCES assay
[PMID: 16828553]
Jurkat IC50
0.35 μM
Compound: 4
Antitumor activity against human jurkat cell line by MTT assay
Antitumor activity against human jurkat cell line by MTT assay
[PMID: 16828553]
MCF7 IC50
6.6 μM
Compound: 4
Antitumor activity against human MCF7 cell line by RTCES assay
Antitumor activity against human MCF7 cell line by RTCES assay
[PMID: 16828553]
MDA-MB-231 IC50
2.4 μM
Compound: 4
Antitumor activity against human M231 cell line by RTCES assay
Antitumor activity against human M231 cell line by RTCES assay
[PMID: 16828553]
NCI-H460 IC50
5.1 μM
Compound: 4
Antitumor activity against human H460 cell line by RTCES assay
Antitumor activity against human H460 cell line by RTCES assay
[PMID: 16828553]
OVCAR-4 IC50
1.4 μM
Compound: 4
Antitumor activity against human OVACR4 cell line by RTCES assay
Antitumor activity against human OVACR4 cell line by RTCES assay
[PMID: 16828553]
体外研究
(In Vitro)

Dibenzyl trisulfide (0.1-50 µM; 2 weeks) 抑制 CRL-2335 细胞增殖和迁移[1]。
Dibenzyl trisulfide (10, 50 µM) 以剂量依赖性方式降低 BAK-1 和 LTA 的 mRNA 和蛋白表达[1]。
Dibenzyl trisulfide (10 µM; 48 h) 诱导 CRL-2335 细胞中溶酶体膜通透性和组织蛋白酶 B 释放[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Dibenzyl trisulfide 相关抗体:

Cell Proliferation Assay[1]

Cell Line: CRL-2335 cells
Concentration: 0.1, 0.5, 1, 10, 50 µM
Incubation Time: 2 weeks
Result: Inhibited proliferation and migration of CRL-2335 cell in a dose-dependent manner.

RT-PCR[1]

Cell Line: CRL-2335 cells
Concentration: 0, 10, 50 µM
Incubation Time: 48 h
Result: Decreased the mRNA expression of BAK-1, GADD45a, and LTA in a dose-dependent manner.

Immunofluorescence[1]

Cell Line: CRL-2335 cells
Concentration: 0, 10, 50 µM
Incubation Time: 48 h
Result: Decreased the protein expression of BAK-1 and LTA but not GADD45a.
分子量

278.46

Formula

C14H14S3
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dibenzyl trisulfide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dibenzyl trisulfide6493-73-8DTSCathepsinRL-2335 cellsBAK-1LTAcathepsin BInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Dibenzyl trisulfide
目录号：
HY-129461
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z