2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. DL-AP4 sodium

DL-AP4 sodium  (Synonyms: 2-Amino-4-phosphonobutyric acid sodium)

目录号: HY-110070
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DL-AP4 sodium (2-Amino-4-phosphonobutyric acid sodium) 是代谢型谷氨酸受体 (mGluR) 的激动剂。DL-AP4 sodium 与 mGluR4 结合，激活与腺苷酸环化酶 (adenylate cyclase) 呈负相关的信号通路，并抑制 Forskolin (HY-15371) 诱导的 cAMP 产生。DL-AP4 sodium 还是 ON 通道的抑制剂，可降低光感受器对亮度变化的敏感性。

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DL-AP4 sodium Chemical Structure

DL-AP4 sodium Chemical Structure

CAS No. : 1263093-79-3

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DL-AP4 sodium 的其他形式现货产品:

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DL-AP4 sodium 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DL-AP4 sodium (2-Amino-4-phosphonobutyric acid sodium) is an agonist for metabotropic glutamate receptors (mGluR). DL-AP4 sodium binds to mGluR4, activates the signaling pathway that is negatively correlated with adenylate cyclase, and inhibits the Forskolin (HY-15371)-induced production of cAMP. DL-AP4 sodium is also an inhibitor for ON channel, that reduces the sensitivity of photoreceptors to brightness changes[1][2].

分子量

205.08

Formula

C4H9NNaO5P
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DL-AP4 sodium 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DL-AP41263093-79-32-Amino-4-phosphonobutyric acidmGluRMetabotropic glutamate receptorsstroketraumaepilepsymacaquesInhibitorinhibitorinhibit

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