2. Neuronal Signaling
  3. Cholinesterase (ChE) Monoamine Oxidase
  4. Dual AChE-MAO B-IN-2

Dual AChE-MAO B-IN-2 是一种有效的 AChE 和 MAO B 双重抑制剂，IC50 值分别为 0.12 µM 和 0.01 µM。Dual AChE-MAO B-IN-2 具有阿尔茨海默病的研究潜力。

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Dual AChE-MAO B-IN-2 Chemical Structure

Dual AChE-MAO B-IN-2 Chemical Structure

CAS No. : 1801157-64-1

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Dual AChE-MAO B-IN-2 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

查看 Monoamine Oxidase 亚型特异性产品:

查看所有亚型
MAO-A MAO-B

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dual AChE-MAO B-IN-2 is a potent AChE and MAO B dual inhibitor with IC50s of 0.12 µM and 0.01 µM for b>AChE and MAO B, respectively. Dual AChE-MAO B-IN-2 has the potential for the research of Alzheimer’s disease[1].

IC50 & Target

MAO-B

4.5 μM (Ki)

体外研究
(In Vitro)

Dual AChE-MAO B-IN-2 (compound 1) shows a +5.5 °C increase in the MAO B enzyme Tm value[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Dual AChE-MAO B-IN-2 相关抗体:
分子量

415.48

Formula

C26H25NO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dual AChE-MAO B-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dual AChE-MAO B-IN-21801157-64-1Cholinesterase (ChE)Monoamine OxidaseMAOTm valuedual reversible coumarinshape complementarityMultitarget directed ligands (MTDLs)Alzheimer’s diseaseInhibitorinhibitorinhibit

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