1. JAK/STAT Signaling Protein Tyrosine Kinase/RTK PI3K/Akt/mTOR
  2. EGFR Akt
  3. EGFR/Akt-IN-1

EGFR/Akt-IN-1 (compound 17) 是 EGFR/Akt 的有效抑制剂,在 A549 细胞中的 IC50 分别为 12.89 μM 和 10.88 μM。EGFR/Akt-IN-1 将细胞周期停滞在 S 期。

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EGFR/Akt-IN-1 Chemical Structure

EGFR/Akt-IN-1 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

EGFR/Akt-IN-1 (compound 17) is a potent inhibitor of EGFR/Akt, with the IC50s of 12.89 μM and 10.88 μM in A549 cells, respectively. EGFR/Akt-IN-1 arrestes the cell cycle at the S phase[1].

分子量

415.47

Formula

C22H17N5O2S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
EGFR/Akt-IN-1
目录号:
HY-161891
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