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Ferrous bisglycinate  (Synonyms: 甘氨酸亚铁)

目录号: HY-130078 纯度: ≥98.0%
COA 产品使用指南

Ferrous bisglycinate 是一种具有口服活性的铁强化剂和补充剂。Ferrous bisglycinate 可用于缺铁性贫血的研究。

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Ferrous bisglycinate Chemical Structure

Ferrous bisglycinate Chemical Structure

CAS No. : 20150-34-9

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500 mg ¥350
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia[1][2].

体外研究
(In Vitro)

Ferrous bisglycinate (25-200 μM; 2 h) does not affect the Caco-2 cells viability[2].
Ferrous bisglycinate (25 μM; 2 h) increases ferritin content in the Caco-2 cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[2]

Cell Line: Caco-2 cells
Concentration: 0, 25, 50, 100, 200 μM
Incubation Time: 2 hours
Result: Did not affect the viability of wild-type and divalent metal transporter 1 (DMT1) knockout Caco-2 cells.

Western Blot Analysis[2]

Cell Line: Caco-2 cells
Concentration: 25 μM
Incubation Time: 2 hours
Result: Increased ferritin content and decreased DMT1 expression levels significantly in the wild-type cells.
体内研究
(In Vivo)

Ferrous bisglycinate (500 mg/kg iron; p.o.) exerts a protective effect on colitis in mice[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female C57BL/6 mice are induced colitis by dextran sodium sulfate (DSS)[3]
Dosage: 500 mg/kg iron
Administration: P.o. (add to the diet) for 10 days
Result: Had the best survival rates (100%).
Caused the least body lost (9% body loss).
Clinical Trial
分子量

203.96

Formula

C4H8FeN2O4

CAS 号
性状

固体

颜色

Light brown to green

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶解性数据
细胞实验: 

0.1 M HCL 中的溶解度 : 2 mg/mL (9.81 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.9029 mL 24.5146 mL 49.0292 mL
5 mM 0.9806 mL 4.9029 mL 9.8058 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物实验:

以下溶解方案,请直接配制工作液。建议现用现配,在短期内尽快用完。 以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比; 如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶。

  • 方案 一

    请依序添加每种溶剂: PBS

    Solubility: 2 mg/mL (9.81 mM); 澄清溶液; 超声助溶 (<60°C)

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥98.0%

参考文献

Ferrous bisglycinate 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
0.1 M HCL 1 mM 4.9029 mL 24.5146 mL 49.0292 mL 122.5730 mL
5 mM 0.9806 mL 4.9029 mL 9.8058 mL 24.5146 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Ferrous bisglycinate
目录号:
HY-130078
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