1. Anti-infection
  2. Bacterial Parasite Antibiotic
  3. G-418

G-418  (Synonyms: Geneticin; Antibiotic G-418)

目录号: HY-108718
产品使用指南 技术支持

G-418 (Geneticin) 是一种氨基糖苷类抗生素,结构类似庆大霉素。它对真核和原核细胞都有毒性,通过干扰蛋白质合成而起作用。

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G-418 Chemical Structure

G-418 Chemical Structure

CAS No. : 49863-47-0

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规格 是否有货
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G-418 的其他形式现货产品:

Customer Review

Other Forms of G-418:

MCE 顾客使用本产品发表的 34 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis[1].

IC50 & Target

Aminoglycoside

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Sf21 IC50
2 μM
Compound: G418
Inhibition of ribosomal activity in Spodoptera frugiperda Sf21 cells assessed as inhibition of translation after 60 mins by fluorescence assay
Inhibition of ribosomal activity in Spodoptera frugiperda Sf21 cells assessed as inhibition of translation after 60 mins by fluorescence assay
[PMID: 20409719]
体外研究
(In Vitro)

G-418 (500 μg/mL,12 days) 用于筛选耐药性 LNCaP 细胞[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

496.55

Formula

C20H40N4O10

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
G-418
目录号:
HY-108718
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