2. Gene
  3. AHSA1 - activator of HSP90 ATPase activity 1 Gene

AHSA1 - activator of HSP90 ATPase activity 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：HSP90 ATPase 活性激活因子 1

种属: Homo sapiens

同用名: p38; AHA1; hAha1; C14orf3

基因 ID: 10598 | 基因类型: protein coding

关于 AHSA1

Cytogenetic location: 14q24.3 Genomic coordinates (GRCh38): 14:77,457,867-77,469,472 (from NCBI)

This gene has 13 transcripts (splice variants) and 232 orthologues. Ubiquitous expression in testis (RPKM 60.3), adrenal (RPKM 41.8) and 25 other tissues.

功能概要

启用 ATPase 激活剂活动； HSP90 蛋白结合活性；和伴侣结合活性。参与 ATPase 活性的正向调节。位于胞质溶胶中。 [由基因组资源联盟提供，2022 年 4 月]

Enables ATPase activator activity; HSP90 protein binding activity; and chaperone binding activity. Involved in positive regulation of ATPase activity. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

AHSA1 基因产物(4)

mRNA Protein Name
NM_001321441.2 NP_001308370.1 activator of 90 kDa heat shock protein ATPase homolog 1 isoform 2
NM_012111.3 NP_036243.1 activator of 90 kDa heat shock protein ATPase homolog 1 isoform 1
NM_001321441.2 NP_001308370.1 activator of 90 kDa heat shock protein ATPase homolog 1 isoform 2
NM_012111.3 NP_036243.1 activator of 90 kDa heat shock protein ATPase homolog 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATPase activator activity IDA
IDA: 通过直接分析推断
12504007 GOA
enables Hsp90 protein binding IPI
IPI: 通过物理相互作用推断
29127155 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
12604615 GOA
enables protein-folding chaperone binding IDA
IDA: 通过直接分析推断
12504007 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of ATP-dependent activity IDA
IDA: 通过直接分析推断
29127155 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

AHSA1 蛋白结构

Aha1_N

Aha1_N: Activator of Hsp90 ATPase, N-terminal (29 - 161)

AHSA1

AHSA1: Activator of Hsp90 ATPase homolog 1-like protein (217 - 331)

  • 0
  • 100
  • 200
  • 300
  • 338 a.a.
蛋白主名 其他名称

activator of 90 kDa heat shock protein ATPase homolog 1

AHA1, activator of heat shock 90kDa protein ATPase homolog 1

AHSA1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
AHSA1 O95433 HSP90AA1 Homo sapiens P07900
Y2H
12604615
种属内
AHSA1 O95433 HSP90AA1 Homo sapiens P07900
Anti Tag CoIP
35271311
种属内
AHSA1 O95433 HSP90AB1 Homo sapiens P08238
Anti Tag CoIP
35271311
种属内
AHSA1 O95433 HSP90AB1 Homo sapiens P08238
Anti Tag CoIP
25036637
种属内
AHSA1 O95433 GCH1 Homo sapiens P30793
Pull Down
16696853
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Stomatitis
Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00485 AHSA1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris AHSA1 VGNC VGNC:37730
Felis catus AHSA1 VGNC VGNC:59696
Mus musculus AHSA1 MGD MGI:2387603
Macaca mulatta AHSA1 VGNC VGNC:69601
Rattus norvegicus AHSA1 RGD RGD:1589285
Bos taurus AHSA1 VGNC VGNC:25755
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