1. Gene
  2. Lims1 - LIM and senescent cell antigen-like domains 1 Gene

Lims1 - LIM and senescent cell antigen-like domains 1 Gene

种属: Mus musculus

同用名: PINCH; Lims1l; PINCH1; 2310016J22Rik; 4921524A02Rik; C430041B13Rik

基因 ID: 110829 | 基因类型: protein coding

关于 Lims1

功能概要

Predicted to enable protein kinase binding activity and zinc ion binding activity. Acts upstream of or within several processes, including cell-matrix adhesion; negative regulation of cell population proliferation; and positive regulation of integrin-mediated signaling pathway. Located in focal adhesion. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and liver and biliary system. Orthologous to human LIMS1 (LIM zinc finger domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Lims1 基因产物(6)

mRNA Protein Name
NM_001193303.1 NP_001180232.1 LIM and senescent cell antigen-like-containing domain protein 1 isoform 3
NM_001346676.1 NP_001333605.1 LIM and senescent cell antigen-like-containing domain protein 1 isoform 4
NM_001359115.1 NP_001346044.1 LIM and senescent cell antigen-like-containing domain protein 1 isoform 5
NM_001359116.1 NP_001346045.1 LIM and senescent cell antigen-like-containing domain protein 1 isoform 6
NM_026148.4 NP_080424.2 LIM and senescent cell antigen-like-containing domain protein 1 isoform 1
NM_201242.1 NP_957694.1 LIM and senescent cell antigen-like-containing domain protein 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12432066 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell-cell adhesion IMP
IMP: 通过突变表型推断
15976450 MGI
acts upstream of or within cell-cell junction organization IGI
IGI: 通过遗传相互作用推断
19652092 MGI
acts upstream of or within cell-matrix adhesion IMP
IMP: 通过突变表型推断
15976450 MGI
acts upstream of cholangiocyte proliferation IGI
IGI: 通过遗传相互作用推断
24058607 MGI
acts upstream of or within chordate embryonic development IMP
IMP: 通过突变表型推断
15798193 MGI
acts upstream of or within establishment or maintenance of cell polarity IMP
IMP: 通过突变表型推断
15976450 MGI
acts upstream of hepatocyte apoptotic process IGI
IGI: 通过遗传相互作用推断
24058607 MGI
acts upstream of integrin-mediated signaling pathway IGI
IGI: 通过遗传相互作用推断
19652092 MGI
acts upstream of or within negative regulation of cholangiocyte proliferation IGI
IGI: 通过遗传相互作用推断
24058607 MGI
acts upstream of or within negative regulation of hepatocyte apoptotic process IGI
IGI: 通过遗传相互作用推断
24058607 MGI
acts upstream of or within negative regulation of hepatocyte proliferation IGI
IGI: 通过遗传相互作用推断
24058607 MGI
acts upstream of or within negative regulation of neural precursor cell proliferation IGI
IGI: 通过遗传相互作用推断
24719101 MGI
acts upstream of neural precursor cell proliferation IGI
IGI: 通过遗传相互作用推断
24719101 MGI
acts upstream of or within positive regulation of integrin-mediated signaling pathway IGI
IGI: 通过遗传相互作用推断
19652092 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in focal adhesion IDA
IDA: 通过直接分析推断
12432066 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

LIM and senescent cell antigen-like-containing domain protein 1

particularly interesting new Cys-His protein 1

重组 Lims1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72064 LIMS1 Protein, Mouse (Baculovirus, His) Q99JW4 (A2-K325) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lims1 NCBI NCBI:3987