PTP4A3 - protein tyrosine phosphatase 4A3 Gene

中文名称：蛋白酪氨酸磷酸酶 4A3

种属: Homo sapiens

同用名: PRL3; PRL-3; PRL-R

关于 PTP4A3

功能概要

该基因编码蛋白酪氨酸磷酸酶家族的一个成员。蛋白酪氨酸磷酸酶是细胞信号分子，在多种细胞过程中发挥调节作用。对小鼠中此类蛋白酪氨酸磷酸酶的研究表明，它们在体内被异戊二烯化，表明它们与细胞质膜有关。编码的蛋白质可以增强细胞增殖，并且该基因的过表达与肿瘤转移有关。可变剪接导致多个转录本变体。[RefSeq 提供，2013 年 7 月]

This gene encodes a member of the protein-tyrosine Phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine Phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]