WDHD1 - WD repeat and HMG-box DNA binding protein 1 Gene

中文名称：WD 重复序列和 HMG-box DNA 结合蛋白 1

种属: Homo sapiens

同用名: AND1; CTF4; AND-1; CHTF4

关于 WDHD1

功能概要

该基因编码的蛋白质包含多个 N 端 WD40 结构域和一个 C 端高迁移率基团 (HMG) 盒。 WD40 结构域存在于多种真核蛋白质中，可作为信号转导、pre-mRNA 加工和细胞骨架组装中的衔接子/调节模块发挥作用。 HMG 盒存在于许多参与染色质组装、转录和复制的真核蛋白质中。可变剪接导致编码不同异构体的两个转录变体。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and Cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]