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  2. CD300A - CD300a molecule Gene

CD300A - CD300a molecule Gene

中文名称:CD300a 分子

种属: Homo sapiens

同用名: IRC1; IRC2; CLM-8; IRp60; IGSF12; CMRF35H; CMRF-35H; CMRF35-H; CMRF35H9; CMRF35-H9; IRC1/IRC2; CMRF-35-H9

基因 ID: 11314 | 基因类型: protein coding

关于 CD300A

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,466,373-74,484,798 (from NCBI)

This gene has 7 transcripts (splice variants), 91 orthologues and 13 paralogues. Broad expression in spleen (RPKM 24.5), appendix (RPKM 12.1) and 14 other tissues.

功能概要

该基因编码的细胞表面蛋白 CD300 糖蛋白家族成员在参与免疫反应信号通路的白细胞上发现。该基因位于 17 号染色体上,与除一个其他家族成员外的所有其他成员位于一个簇中。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供,2012 年 2 月]

This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the Other family members. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

CD300A 基因产物(4)

mRNA Protein Name
NM_001256841.2 NP_001243770.1 CMRF35-like molecule 8 isoform 2 precursor
NM_001330456.1 NP_001317385.1 CMRF35-like molecule 8 isoform 3
NM_001330457.2 NP_001317386.1 CMRF35-like molecule 8 isoform 4 precursor
NM_007261.4 NP_009192.2 CMRF35-like molecule 8 isoform 1 precursor

CD300A 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (19 - 112)

SIT

SIT: SHP2-interacting transmembrane adaptor protein, SIT (181 - 275)

  • 0
  • 100
  • 200
  • 299 a.a.
蛋白主名 其他名称

CMRF35-like molecule 8

CD300 antigen-like family member A

CD300A 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CD300A Q9UGN4 KRT38 Homo sapiens O76015 25416956
种属内
CD300A Q9UGN4 KRT38 Homo sapiens O76015 25416956
种属内
CD300A Q9UGN4 CD300LB Homo sapiens A8K4G0 20959446
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 CD300A 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70754 CD300a/LMIR1 Protein, Human (HEK293, Fc-His) Q9UGN4-1 (L18-Q178) ≥95%
HY-P72738 CD300a/LMIR1 Protein, Human (HEK293, His) Q9UGN4-1 (L18-Q178) ≥95%

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CD300A RGD RGD:1583719
Macaca mulatta CD300A VGNC VGNC:104592
Mus musculus CD300A MGD MGI:2443411
Macaca fascicularis CD300A NCBI NCBI:102124907
Others CD300A NCBI