1. Gene
  2. TMEM106A - transmembrane protein 106A Gene

TMEM106A - transmembrane protein 106A Gene

中文名称:跨膜蛋白 106A

种属: Homo sapiens

基因 ID: 113277 | 基因类型: protein coding

关于 TMEM106A

This gene has 8 transcripts (splice variants) and 111 orthologues. Broad expression in kidney (RPKM 9.2), appendix (RPKM 4.7) and 23 other tissues.

功能概要

预计参与多个过程,包括糖蛋白生物合成过程;细胞因子产生的正调节;和细胞内信号转导的正调控。预测位于质膜中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in several processes, including glycoprotein biosynthetic process; positive regulation of cytokine production; and positive regulation of intracellular signal transduction. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM106A 基因产物(4)

mRNA Protein Name
NM_001291586.2 NP_001278515.1 transmembrane protein 106A isoform a
NM_001291587.2 NP_001278516.1 transmembrane protein 106A isoform b
NM_001291588.2 NP_001278517.1 transmembrane protein 106A isoform c
NM_145041.4 NP_659478.1 transmembrane protein 106A isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

TMEM106A 蛋白结构

DUF1356

DUF1356: Protein of unknown function (DUF1356) (13 - 252)

  • 0
  • 100
  • 200
  • 262 a.a.
蛋白主名 其他名称

transmembrane protein 106A

TMEM106A 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TMEM106A Q96A25 TNMD Homo sapiens Q9H2S6-2
Validated Y2H
32296183
种属内
TMEM106A Q96A25 TMEM106C Homo sapiens Q9BVX2
Y2H Prey Pooling
32296183
种属内
TMEM106A Q96A25 TMEM106C Homo sapiens Q9BVX2
Validated Y2H
32296183
种属内
TMEM106A Q96A25 TMEM106C Homo sapiens Q9BVX2
Y2H Array
32296183
种属内
TMEM106A Q96A25 TMEM106C Homo sapiens Q9BVX2
Anti Tag CoIP
33961781
种属内
TMEM106A Q96A25 ERG28 Homo sapiens Q9UKR5
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Hereditary Breast Ovarian Cancer Syndrome

Hereditary Breast And Ovarian Cancer Syndrome

Brca1- And Brca2-Associated Hereditary Breast And Ovarian Cancer

Breast And/Or Ovarian Cancer

Breast And Ovarian Cancer Syndrome

Hboc Syndrome

Hereditary Breast And Ovarian Cancer

Brca1- Brca2-Associated Hboc

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TMEM106A VGNC VGNC:47446
Rattus norvegicus TMEM106A RGD RGD:1309043
Bos taurus TMEM106A VGNC VGNC:35944
Mus musculus TMEM106A MGD MGI:1922056
Macaca mulatta TMEM106A VGNC VGNC:79695
Felis catus TMEM106A VGNC VGNC:66256