ACOT7 - acyl-CoA thioesterase 7 Gene

中文名称：酰基辅酶 A 硫酯酶 7

种属: Homo sapiens

同用名: ACT; ACH1; BACH; LACH; LACH1; hBACH; CTE-II

基因 ID: 11332 | 基因类型: protein coding

关于 ACOT7

Cytogenetic location: 1p36.31 Genomic coordinates (GRCh38): 1:6,264,272-6,393,767 (from NCBI)

This gene has 10 transcripts (splice variants), 194 orthologues and 2 paralogues. Broad expression in brain (RPKM 26.5), kidney (RPKM 21.3) and 22 other tissues.

功能概要

该基因编码酰基辅酶家族的一个成员。编码的蛋白质水解棕榈酰辅酶 A 和其他长链脂肪酸的辅酶 A 硫酯。该基因表达减少可能与内侧颞叶癫痫有关。编码具有不同亚细胞位置的不同亚型的选择性剪接转录变体已经被表征。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA thioester of palmitoyl-CoA and Other long-chain fatty acids. Decreased expression of this gene may be associated with mesial temporal lobe epilepsy. Alternatively spliced transcript variants encoding distinct isoforms with different subcellular locations have been characterized. [provided by RefSeq, Jul 2008]

ACOT7 基因产物(4)

mRNA	Protein	Name
NM_007274.4	NP_009205.3	cytosolic acyl coenzyme A thioester hydrolase isoform hBACHa
NM_181864.3	NP_863654.1	cytosolic acyl coenzyme A thioester hydrolase isoform hBACHb
NM_181865.3	NP_863655.1	cytosolic acyl coenzyme A thioester hydrolase isoform hBACHc
NM_181866.3	NP_863656.1	cytosolic acyl coenzyme A thioester hydrolase isoform hBACHd

ACOT7 蛋白结构

4HBT

0
100
200
300
380 a.a.

蛋白主名

其他名称

cytosolic acyl coenzyme A thioester hydrolase

CTE-IIa

ACOT7 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	ACOT7	O00154	UBQLN1	Homo sapiens	Q9UMX0-2	Y2H Prey Pooling	25416956
种属内	ACOT7	O00154	HEL-S-101	Homo sapiens	V9HW27	Validated Y2H	25416956
种属内	ACOT7	O00154	HEL-S-101	Homo sapiens	V9HW27	Y2H Array	25416956
种属内	ACOT7	O00154	MAGEA6	Homo sapiens	P43360	Y2H Prey Pooling	25416956
种属内	ACOT7	O00154	MAGEA6	Homo sapiens	P43360	Validated Y2H	25416956
种属内	ACOT7	O00154	CAMK2B	Homo sapiens	Q13554	Validated Y2H	25416956
种属内	ACOT7	O00154	CAMK2B	Homo sapiens	Q13554	Y2H Array	25416956
种属内	ACOT7	O00154	CHD8	Homo sapiens	Q9HCK8	Crosslink	26949739
种属内	ACOT7	O00154	FMR1	Homo sapiens	Q06787	Crosslink	26949739
种属内	ACOT7	O00154	CUL3	Homo sapiens	Q13618	Crosslink	26949739
种属内	ACOT7	O00154	UBQLN1	Homo sapiens	Q9UMX0	Validated Y2H	25416956
种属内	ACOT7	O00154	UBQLN1	Homo sapiens	Q9UMX0	Y2H Array	25416956
种属内	ACOT7	O00154	UBQLN1	Homo sapiens	Q9UMX0	Y2H Prey Pooling	25416956
种属内	ACOT7	O00154	THAP1	Homo sapiens	Q9NVV9	Y2H Prey Pooling	25416956
种属内	ACOT7	O00154	THAP1	Homo sapiens	Q9NVV9	Y2H Array	25416956
种属内	ACOT7	O00154	ANK2	Homo sapiens	Q01484	Crosslink	26949739

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Temporal Lobe Epilepsy

Epilepsy, Temporal Lobe

Epilepsy Temporal Lobe

Hyperinsulinemic Hypoglycemia, Familial, 7

HHF7	Exercise-Induced Hyperinsulinemic Hypoglycemia
Exercise-Induced Hyperinsulinism	Familial Hyperinsulinemic Hypoglycemia 7
Eihi	Hyperinsulinism Due To Monocarboxylate Transporter 1 Deficiency
Hyperinsulinism Due To Slc16a1 Deficiency	Hyperinsulinemic Hypoglycemia, Exercise-Induced
Exercise Induced Hyperinsulinemic Hypoglycemia	Hyperinsulinemic Hypoglycemia Exercise-Induced
Hyperinsulinemic Hypoglycemia Familial 7

Pontocerebellar Hypoplasia, Type 16

PCH16	Pontocerebellar Hypoplasia Type 16
Pontocerebellar Hypoplasia 16	Doid:0112333

Epilepsy

Epilepsy Syndrome	Epileptic Syndrome
Epilepsies	Symptomatic Epilepsies
Post Traumatic Epilepsy	Traumatic Epilepsy
Traumatic Epileptic	Epilepsy Due To Hippocampal Sclerosis
Epilepsy With Ammon'S Horn Sclerosis	Epilepsy Due To Cortical Dysplasia
Epilepsy Due To Neuronal Migration Disorders

Leukoencephalopathy With Vanishing White Matter

Cree Leukoencephalopathy	Vanishing White Matter Disease
Ovarioleukodystrophy	Vanishing White Matter Leukodystrophy
Childhood Ataxia With Central Nervous System Hypomyelinization	Cach
Cach Syndrome	Myelinosis Centralis Diffusa
VWM	Cle
Childhood Ataxia With Central Nervous System Hypomyelination	Childhood Ataxia With Diffuse Central Nervous System Hypomyelination
Cach/Vwm	Cach/Vwm Syndrome
Childhood Ataxia With Central Nervous System Hypomyelination/Vanishing White Matter	Cree Leukoencehalopathy
Late Infantile Cach Syndrome	Juvenile Or Adult Cach Syndrome
Congenital Or Early Infantile Cach Syndrome	Leukodystrophy With Vanishing White Matter

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS00179	ACOT7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	ACOT7	RGD	RGD:628856
Canis familiaris	ACOT7	VGNC	VGNC:53259
Felis catus	ACOT7	VGNC	VGNC:82524
Macaca mulatta	ACOT7	VGNC	VGNC:99835
Mus musculus	ACOT7	MGD	MGI:1917275

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

ACOT7 - acyl-CoA thioesterase 7 Gene

关于 ACOT7

功能概要

ACOT7 基因产物(4)

ACOT7 蛋白结构

ACOT7 蛋白互作信息

关联疾病

直系同源

热门区域

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ACOT7 - acyl-CoA thioesterase 7 Gene

关于 ACOT7

功能概要

ACOT7 基因产物(4)

ACOT7 蛋白结构

ACOT7 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z