2. Gene
  3. TUSC2 - tumor suppressor 2, mitochondrial calcium regulator Gene

TUSC2 - tumor suppressor 2, mitochondrial calcium regulator Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肿瘤抑制因子 2，线粒体钙调节因子

种属: Homo sapiens

同用名: PAP; FUS1; PDAP2; C3orf11

基因 ID: 11334 | 基因类型: protein coding

关于 TUSC2

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:50,324,909-50,328,223 (from NCBI)

This gene has 6 transcripts (splice variants) and 285 orthologues. Ubiquitous expression in brain (RPKM 15.7), kidney (RPKM 12.1) and 25 other tissues.

功能概要

该基因是高度保守的肺癌候选基因。目前没有关于该基因的其他信息。[RefSeq 提供，2008 年 7 月]

This gene is a highly conserved lung Cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008]

TUSC2 基因产物(1)

mRNA Protein Name
NM_007275.3 NP_009206.1 tumor suppressor candidate 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TUSC2 蛋白结构

TUSC2

TUSC2: Tumour suppressor candidate 2 (1 - 109)

  • 0
  • 100
  • 110 a.a.
蛋白主名 其他名称

tumor suppressor candidate 2

PDGFA-associated protein 2

TUSC2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra TUSC2 O75896 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra TUSC2 O75896 MDFI Homo sapiens Q99750
Validated Y2H
25416956
Intra TUSC2 O75896 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Intra TUSC2 O75896 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra TUSC2 O75896 MDFI Homo sapiens Q99750
Y2H Prey Pooling
25416956
Intra TUSC2 O75896 RBPMS Homo sapiens Q93062
Y2H Array
25416956
Intra TUSC2 O75896 FHL5 Homo sapiens Q5TD97
Y2H Prey Pooling
32296183
Intra TUSC2 O75896 FHL5 Homo sapiens Q5TD97
Validated Y2H
32296183
Intra TUSC2 O75896 FHL5 Homo sapiens Q5TD97
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15274 TUSC2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus TUSC2 MGD MGI:1931086
Rattus norvegicus TUSC2 RGD RGD:1561664
Macaca mulatta TUSC2 VGNC VGNC:110321
Bos taurus TUSC2 VGNC VGNC:53155
Felis catus TUSC2 VGNC VGNC:97674
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