Casp4 - caspase 4 Gene

中文名称：半胱天冬酶 4

种属: Rattus norvegicus

同用名: Casp11

关于 Casp4

功能概要

该基因编码的蛋白可启动支架蛋白结合活性。预计参与多个过程，包括对淀粉样蛋白-β 的细胞反应；肿瘤坏死因子介导的信号通路的正向调控；和蛋白质自动加工。预计在异位生殖细胞程序性细胞死亡的上游或内部起作用；白细胞介素 1 β 生成的正向调节；和细胞焦亡。位于神经元投射区和神经元细胞体中。部分含蛋白质复合物。与人类 CASP4（caspase 4）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables scaffold protein binding activity. Predicted to be involved in several processes, including cellular response to amyloid-beta; positive regulation of tumor necrosis factor-mediated signaling pathway; and protein autoprocessing. Predicted to act upstream of or within ectopic germ cell programmed cell death; positive regulation of interleukin-1 beta production; and Pyroptosis. Located in neuron projection and neuronal cell body. Part of protein-containing complex. Orthologous to human CASP4 (Caspase 4). [provided by Alliance of Genome Resources, Apr 2022]