2. Gene
  3. Gla - galactosidase, alpha Gene

Gla - galactosidase, alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ags

基因 ID: 11605 | 基因类型: protein coding

关于 Gla

功能概要

Enables alpha-galactosidase activity. Involved in negative regulation of nitric oxide biosynthetic process and negative regulation of nitric-oxide synthase activity. Acts upstream of or within glycosylceramide catabolic process. Located in extracellular space and lysosome. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and liver and biliary system. Used to study Fabry disease. Human ortholog(s) of this gene implicated in Fabry disease. Orthologous to human GLA (galactosidase alpha). [provided by Alliance of Genome Resources, Apr 2022]

Gla 基因产物(1)

mRNA Protein Name
NM_013463.3 NP_038491.2 alpha-galactosidase A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alpha-galactosidase activity IDA
IDA: 通过直接分析推断
198184 MGI
enables alpha-galactosidase activity IMP
IMP: 通过突变表型推断
9122231 MGI
enables hydrolase activity IDA
IDA: 通过直接分析推断
19710420 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within aorta development IMP
IMP: 通过突变表型推断
32428018 MGI
NOT acts upstream of or within bone mineralization IMP
IMP: 通过突变表型推断
16697974 MGI
acts upstream of or within glycosylceramide catabolic process IDA
IDA: 通过直接分析推断
10840053 MGI
acts upstream of or within glycosylceramide catabolic process IMP
IMP: 通过突变表型推断
9122231 MGI
involved in negative regulation of nitric oxide biosynthetic process IMP
IMP: 通过突变表型推断
15668341 MGI
involved in negative regulation of nitric-oxide synthase activity IMP
IMP: 通过突变表型推断
15668341 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
19710420 MGI
located in lysosome IDA
IDA: 通过直接分析推断
15629890 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

alpha-galactosidase A

alpha-D-galactosidase A

alpha-D-galactoside galactohydrolase

galactosylgalactosylglucosylceramidase GLA

melibiase

重组 Gla 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73077 GLA/alpha-Galactosidase A Protein, Mouse (HEK293, His) Q8BGZ6 (L34-R421) ≥95%

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B2172 Vitamin K 98.70% 否
Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-112499 Menaquinone-7 ≥98.0% Phase 2
HY-112499R Menaquinone-7 (Standard) / Phase 2
Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-118135 4-Methylumbelliferyl-α-D-galactopyranoside 99.76% 否
HY-W009276 γ-Linolenic Acid methyl ester Inducer 99.37% 否
HY-112499S1 Menaquinone-7-13C6 ≥96.0% 否
HY-112499S Menaquinone-7-d7 / 否
HY-144003 BAY-R 1005 / 否
HY-RS05463 GLA Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gla NCBI NCBI:2717
Macaca fascicularis Gla NCBI NCBI:102124721
Rattus norvegicus Gla NCBI NCBI:363494
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z