2. Gene
  3. Gla - galactosidase, alpha Gene

Gla - galactosidase, alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 363494 | 基因类型: protein coding

关于 Gla

功能概要

Enables alpha-galactosidase activity and galactoside binding activity. Predicted to be involved in several processes, including glycosylceramide catabolic process; negative regulation of nitric oxide biosynthetic process; and negative regulation of nitric-oxide synthase activity. Located in lysosome. Used to study Fabry disease and lysosomal storage disease. Human ortholog(s) of this gene implicated in Fabry disease. Orthologous to human GLA (galactosidase alpha). [provided by Alliance of Genome Resources, Apr 2022]

Gla 基因产物(1)

mRNA Protein Name
NM_001108820.3 NP_001102290.2 alpha-galactosidase A
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alpha-galactosidase activity IDA
IDA: 通过直接分析推断
8702598 RGD
enables alpha-galactosidase activity IMP
IMP: 通过突变表型推断
8717430 RGD
enables galactoside binding IDA
IDA: 通过直接分析推断
8702598 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in glycosphingolipid catabolic process IMP
IMP: 通过突变表型推断
34320241 RGD
involved in lipid storage IMP
IMP: 通过突变表型推断
34541380 RGD
involved in platelet activation IMP
IMP: 通过突变表型推断
34320241 RGD
involved in platelet aggregation IMP
IMP: 通过突变表型推断
34320241 RGD
involved in regulation of axon diameter IMP
IMP: 通过突变表型推断
34541380 RGD
involved in regulation of locomotion involved in locomotory behavior IMP
IMP: 通过突变表型推断
36660199 RGD
involved in sleep IMP
IMP: 通过突变表型推断
36660199 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

alpha-galactosidase A

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B2172 Vitamin K 98.70% 否
Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-112499 Menaquinone-7 ≥98.0% Phase 2
HY-112499R Menaquinone-7 (Standard) / Phase 2
Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-118135 4-Methylumbelliferyl-α-D-galactopyranoside 99.76% 否
HY-W009276 γ-Linolenic Acid methyl ester Inducer 99.37% 否
HY-112499S1 Menaquinone-7-13C6 ≥96.0% 否
HY-112499S Menaquinone-7-d7 / 否
HY-144003 BAY-R 1005 / 否
HY-E70535 Des-Gla-Human Activated Protein C / 否
HY-E70536 Des-Gla-Human Factor VIIa / 否
HY-E70537 Des-Gla-Human Factor X / 否
HY-E70538 Des-Gla-Human Factor XaB / 否
HY-E70539 Des-Gla-Human Protein C / 否
HY-E70540 Des-Gla-Human Prothrombin / 否
HY-RS05463 GLA Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gla NCBI NCBI:2717
Macaca fascicularis Gla NCBI NCBI:102124721
Mus musculus Gla NCBI NCBI:11605
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