2. Gene
  3. ACSM1 - acyl-CoA synthetase medium chain family member 1 Gene

ACSM1 - acyl-CoA synthetase medium chain family member 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：酰基辅酶 A 合成酶中链家族成员 1

种属: Homo sapiens

同用名: BUCS1; MACS1

基因 ID: 116285 | 基因类型: protein coding

关于 ACSM1

Cytogenetic location: 16p12.3 Genomic coordinates (GRCh38): 16:20,623,235-20,697,680 (from NCBI)

This gene has 6 transcripts (splice variants), 268 orthologues and 13 paralogues. Broad expression in prostate (RPKM 1.3), ovary (RPKM 1.3) and 18 other tissues.

功能概要

启用 CoA 连接酶活性。预计参与酰基辅酶 A 代谢过程和脂肪酸生物合成过程。位于线粒体基质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables CoA-ligase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid biosynthetic process. Located in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2022]

ACSM1 基因产物(2)

mRNA Protein Name
NM_001318890.3 NP_001305819.1 acyl-coenzyme A synthetase ACSM1, mitochondrial
NM_052956.3 NP_443188.2 acyl-coenzyme A synthetase ACSM1, mitochondrial
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables benzoate-CoA ligase activity IDA
IDA: 通过直接分析推断
10434065 GOA
enables decanoate-CoA ligase activity IDA
IDA: 通过直接分析推断
10434065 GOA
enables long-chain fatty acid-CoA ligase activity IDA
IDA: 通过直接分析推断
11470804 GOA
enables medium-chain fatty acid-CoA ligase activity IDA
IDA: 通过直接分析推断
10434065 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial matrix IDA
IDA: 通过直接分析推断
11470804 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ACSM1 蛋白结构

AMP-binding

AMP-binding: AMP-binding enzyme (68 - 473)

AMP-binding_C

AMP-binding_C: AMP-binding enzyme C-terminal domain (483 - 563)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 577 a.a.
蛋白主名 其他名称

acyl-coenzyme A synthetase ACSM1, mitochondrial

Butyrate CoA ligase

ACSM1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ACSM1 Q08AH1 OSBPL3 Homo sapiens Q9H4L5
Y2H Prey Pooling
32296183
种属内
ACSM1 Q08AH1 OSBPL3 Homo sapiens Q9H4L5
Validated Y2H
32296183
种属内
ACSM1 Q08AH1 OSBPL3 Homo sapiens Q9H4L5
Y2H Array
32296183
种属内
ACSM1 Q08AH1 MTUS2 Homo sapiens Q5JR59-3
Validated Y2H
32296183
种属内
ACSM1 Q08AH1 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
种属内
ACSM1 Q08AH1 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
种属内
ACSM1 Q08AH1 CMTM5 Homo sapiens Q96DZ9-2
Validated Y2H
32296183
种属内
ACSM1 Q08AH1 CMTM5 Homo sapiens Q96DZ9-2
Y2H Array
32296183
种属内
ACSM1 Q08AH1 CMTM5 Homo sapiens Q96DZ9-2
Y2H Prey Pooling
32296183
种属内
ACSM1 Q08AH1 MAGEA2 Homo sapiens P43356
Y2H Prey Pooling
32296183
种属内
ACSM1 Q08AH1 MAGEA2 Homo sapiens P43356
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Breast Apocrine Carcinoma

Apocrine Carcinoma Of Breast

Apocrine Breast Carcinoma
Apocrine Adenocarcinoma

Apocrine Carcinoma

Apocrine Gland Carcinoma

Carcinoma Of The Apocrine Gland

Carcinoma Of Apocrine Gland
Acute Hemorrhagic Leukoencephalitis

Ahl

Acute Haemorrhagic Leucoencephalitis Of Weston Hurst

Leukoencephalitis, Acute Hemorrhagic

Acute Hemorrhagic Encephalomyelitis

Acute Necrotizing Hemorrhagic Leukoencephalitis

Weston-Hurst Syndrome

Ahle

Acute Haemorrhagic Leucoencephalitis

Hurst Disease

Acute Haemorrhagic Leukoencephalitis, Postimmunization Or Postvaccinal

Postimmunization Or Postvaccinal Leukoencephalopathy
Currarino Syndrome

Currarino Triad

Partial Sacral Agenesis With Intact First Sacral Vertebra, Presacral Mass And Anorectal Malformation

CURRAS
Abdominal Obesity-Metabolic Syndrome Quantitative Trait Locus 2

Abdominal Obesity-Metabolic Syndrome

Abdominal Obesity Metabolic Syndrome

Metabolic Syndrome X

Aoms2

Aoms1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00205 ACSM1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus ACSM1 VGNC VGNC:50046
Mus musculus ACSM1 MGD MGI:2152200
Rattus norvegicus ACSM1 RGD RGD:1306813
Macaca mulatta ACSM1 VGNC VGNC:69456
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