1. Gene
  2. ART5 - ADP-ribosyltransferase 5 Gene

ART5 - ADP-ribosyltransferase 5 Gene

中文名称:ADP-核糖基转移酶 5

种属: Homo sapiens

同用名: ARTC5

基因 ID: 116969 | 基因类型: protein coding

关于 ART5

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:3,638,512-3,642,379 (from NCBI)

This gene has 5 transcripts (splice variants), 615 orthologues and 3 paralogues. Biased expression in testis (RPKM 6.5), ovary (RPKM 2.3) and 5 other tissues.

功能概要

该基因编码的蛋白质属于 ARG 特异性 ADP-核糖基转移酶家族。该家族中的蛋白质通过将 ADP-核糖附加到目标蛋白质中的特定氨基酸残基上来调节目标蛋白质的功能。小鼠同源物缺乏糖基磷脂酰肌醇锚定信号序列,预计是一种分泌酶。已发现该基因编码不同亚型的几种转录本。[RefSeq 提供,2014 年 7 月]

The protein encoded by this gene belongs to the ARG-specific ADP-ribosyltransferase family. Proteins in this family regulate the function of target proteins by attaching ADP-ribose to specific amino acid residues in their target proteins. The mouse homolog lacks a glycosylphosphatidylinositol-anchor signal sequence and is predicted to be a secretory Enzyme. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

ART5 基因产物(3)

mRNA Protein Name
NM_001079536.2 NP_001073004.1 ecto-ADP-ribosyltransferase 5 isoform a precursor
NM_001297668.2 NP_001284597.1 ecto-ADP-ribosyltransferase 5 isoform b precursor
NM_053017.5 NP_443750.2 ecto-ADP-ribosyltransferase 5 isoform a precursor

ART5 蛋白结构

ART

ART: NAD:arginine ADP-ribosyltransferase (30 - 254)

  • 0
  • 100
  • 200
  • 291 a.a.
蛋白主名 其他名称

ecto-ADP-ribosyltransferase 5

ADP-ribosyltransferase C2 and C3 toxin-like 5

ART5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ART5 Q96L15 PGRMC2 Homo sapiens O15173 32296183
种属内
ART5 Q96L15 PGRMC2 Homo sapiens O15173 32296183
种属内
ART5 Q96L15 PGRMC2 Homo sapiens O15173 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ART5 VGNC VGNC:69890
Mus musculus ART5 MGD MGI:107948
Rattus norvegicus ART5 RGD RGD:628834
Canis familiaris ART5 VGNC VGNC:38149
Felis catus ART5 VGNC VGNC:59950