2. Gene
  3. Bglap - bone gamma carboxyglutamate protein Gene

Bglap - bone gamma carboxyglutamate protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: OC; BGP; OG1; mOC-A; Bglap1

基因 ID: 12096 | 基因类型: protein coding

关于 Bglap

功能概要

This gene encodes one of the most abundant non-collagenous proteins in bone tissue that is localized to the mineralized matrix of bone. The encoded preproprotein undergoes proteolytic processing and post-translational gamma carboxylation to generate a mature, calcium-binding protein. Mice lacking the encoded protein develop abnormalities of bone remodelling. This gene is located adjacent to two Other osteocalcin-related genes on chromosome 3. [provided by RefSeq, Oct 2015]

Bglap 基因产物(1)

mRNA Protein Name
NM_007541.3 NP_031567.1 osteocalcin preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hormone activity IDA
IDA: 通过直接分析推断
17693256 MGI
enables hormone activity IMP
IMP: 通过突变表型推断
20655470 MGI
enables structural constituent of bone IMP
IMP: 通过突变表型推断
8684484 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in brain development IDA
IDA: 通过直接分析推断
24074871 MGI
involved in brain development IMP
IMP: 通过突变表型推断
24074871 MGI
acts upstream of or within cellular response to BMP stimulus IDA
IDA: 通过直接分析推断
21324897 MGI
involved in cellular response to insulin stimulus IDA
IDA: 通过直接分析推断
17693256 MGI
involved in cellular response to insulin stimulus IMP
IMP: 通过突变表型推断
17693256 MGI
involved in cognition IDA
IDA: 通过直接分析推断
28851741 MGI
involved in cognition IMP
IMP: 通过突变表型推断
28851741 MGI
involved in glucose homeostasis IDA
IDA: 通过直接分析推断
17693256 MGI
involved in glucose homeostasis IMP
IMP: 通过突变表型推断
17693256 MGI
involved in learning or memory IMP
IMP: 通过突变表型推断
24074871 MGI
involved in negative regulation of bone development IMP
IMP: 通过突变表型推断
8684484 MGI
involved in positive regulation of neurotransmitter secretion IDA
IDA: 通过直接分析推断
24074871 MGI
involved in positive regulation of neurotransmitter secretion IMP
IMP: 通过突变表型推断
24074871 MGI
involved in regulation of testosterone biosynthetic process IDA
IDA: 通过直接分析推断
21333348 MGI
involved in regulation of testosterone biosynthetic process IMP
IMP: 通过突变表型推断
21333348 MGI
involved in type B pancreatic cell proliferation IDA
IDA: 通过直接分析推断
17693256 MGI
involved in type B pancreatic cell proliferation IMP
IMP: 通过突变表型推断
17693256 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15030764 MGI
is active in extracellular region IDA
IDA: 通过直接分析推断
20655470 MGI
located in extracellular region IDA
IDA: 通过直接分析推断
21324897 MGI
is active in extracellular region IMP
IMP: 通过突变表型推断
20655470 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

osteocalcin

bone Gla protein

bone gamma carboxyglutamate protein 1

gamma-carboxyglutamic acid-containing protein

重组 Bglap 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72103 BGLAP Protein, Mouse (His-SUMO) P86546 (Y50-I95) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01488 BGLAP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bglap NCBI NCBI:632
Rattus norvegicus Bglap NCBI NCBI:25295
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z