2. Gene
  3. Cbx5 - chromobox 5 Gene

Cbx5 - chromobox 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HP1; Hp1a; Hp1alpha; 2610029O15Rik

基因 ID: 12419 | 基因类型: protein coding

关于 Cbx5

功能概要

Enables several functions, including histone deacetylase binding activity; identical protein binding activity; and methylated histone binding activity. Acts upstream of or within negative regulation of transcription, DNA-templated. Located in chromocenter; chromosomal region; and nucleolus. Part of histone deacetylase complex; Histone Methyltransferase complex; and transcription repressor complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human CBX5 (chromobox 5). [provided by Alliance of Genome Resources, Apr 2022]

Cbx5 基因产物(4)

mRNA Protein Name
NM_001076789.2 NP_001070257.1 chromobox protein homolog 5
NM_001110216.1 NP_001103686.1 chromobox protein homolog 5
NM_001358950.1 NP_001345879.1 chromobox protein homolog 5
NM_007626.3 NP_031652.1 chromobox protein homolog 5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
12242305 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
10318760 MGI
enables histone deacetylase binding IPI
IPI: 通过物理相互作用推断
12242305 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
8978696 MGI
enables methylated histone binding IPI
IPI: 通过物理相互作用推断
16127177 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
8978696 MGI
enables protein-macromolecule adaptor activity IPI
IPI: 通过物理相互作用推断
12242305 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
10562550 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromocenter IDA
IDA: 通过直接分析推断
17284516 MGI
located in chromosome, telomeric region IDA
IDA: 通过直接分析推断
20110566 MGI
located in heterochromatin IDA
IDA: 通过直接分析推断
10318760 MGI
part of histone deacetylase complex IDA
IDA: 通过直接分析推断
12242305 MGI
part of histone methyltransferase complex IDA
IDA: 通过直接分析推断
12242305 MGI
located in kinetochore IDA
IDA: 通过直接分析推断
14519686 MGI
located in nucleolus IDA
IDA: 通过直接分析推断
10318760 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10318760 MGI
located in pericentric heterochromatin IDA
IDA: 通过直接分析推断
20110566 MGI
part of transcription repressor complex IDA
IDA: 通过直接分析推断
12242305 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

chromobox protein homolog 5

HP1 alpha

chromobox homolog 5

heterochromatin protein 1 alpha

heterochromatin protein 1 homolog alpha

mHP1(alpha)

Cbx5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Cbx5 Q61686 Senp7 Mus musculus Q8BUH8
Anti Tag CoIP
22388734
种属内
Cbx5 Q61686 Trim24 Mus musculus Q64127
Y2H
8978696
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-142952 UNC6864 (Kei) Inhibitor / 否
HY-142953 UNC6349 (Ket2) Inhibitor / 否
HY-142954 UNC6212 (Kme2) Inhibitor / 否
HY-RS02012 CBX5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cbx5 NCBI NCBI:23468
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