2. Gene
  3. Cd8a - CD8 antigen, alpha chain Gene

Cd8a - CD8 antigen, alpha chain Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ly-2; Ly-B; Ly-35; Lyt-2

基因 ID: 12525 | 基因类型: protein coding

关于 Cd8a

功能概要

Enables identical protein binding activity. Acts upstream of or within several processes, including cytotoxic T cell differentiation; defense response to virus; and positive regulation of calcium-mediated signaling. Located in external side of plasma membrane. Is expressed in several structures, including endocrine gland; exocrine gland; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human CD8a (CD8a molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd8a 基因产物(2)

mRNA Protein Name
NM_001081110.2 NP_001074579.1 T-cell surface glycoprotein CD8 alpha chain isoform 1 precursor
NM_009857.1 NP_033987.1 T-cell surface glycoprotein CD8 alpha chain isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
15749886 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
7664803 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T cell mediated immunity IMP
IMP: 通过突变表型推断
1673361 MGI
acts upstream of calcium-mediated signaling IDA
IDA: 通过直接分析推断
9208839 MGI
acts upstream of or within cell surface receptor signaling pathway IDA
IDA: 通过直接分析推断
9208839 MGI
acts upstream of or within cytotoxic T cell differentiation IMP
IMP: 通过突变表型推断
1673361 MGI
acts upstream of or within defense response to virus IDA
IDA: 通过直接分析推断
17277142 MGI
acts upstream of or within positive regulation of calcium-mediated signaling IDA
IDA: 通过直接分析推断
9208839 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
14568922 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
1673361 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
22081144 MGI
part of receptor complex IPI
IPI: 通过物理相互作用推断
22081144 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

T-cell surface glycoprotein CD8 alpha chain

Lyt-2.1 lymphocyte differentiation antigen (AA at 100)

T-cell surface glycoprotein Lyt-2

重组 Cd8a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74259 CD8A-CD8B Heterodimer Protein, Mouse (HEK293, Flag-His) P01731 (K28-Y196)&P10300 (L22-T175) ≥95%
HY-P74268 CD8 alpha Protein, Mouse (HEK293, His) P01731/NP_001074579.1 (K28-Y196) ≥95%
HY-P74269 CD8 alpha Protein, Mouse (HEK293, Fc) P01731-1 (K28-Y196) ≥95%
HY-P77520 CD8 alpha Protein, Mouse (Biotinylated, HEK293, His) P01731-1 (K28-Y196) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02275 CD8A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd8a NCBI NCBI:925
Macaca fascicularis Cd8a NCBI NCBI:102124337
Rattus norvegicus Cd8a NCBI NCBI:24930
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