2. Gene
  3. Cdh2 - cadherin 2 Gene

Cdh2 - cadherin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CDHN; Ncad; N-CAD

基因 ID: 12558 | 基因类型: protein coding

关于 Cdh2

功能概要

This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion. The encoded preproprotein undergoes proteolytic processing to generate a mature protein. Mice lacking the encoded protein exhibit severe developmental defects resulting in embryonic death. [provided by RefSeq, Oct 2015]

Cdh2 基因产物(1)

mRNA Protein Name
NM_007664.5 NP_031690.3 cadherin-2 preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA binding IDA
IDA: 通过直接分析推断
27783602 MGI
enables calcium ion binding IDA
IDA: 通过直接分析推断
9655503 MGI
enables enzyme binding IPI
IPI: 通过物理相互作用推断
24952463 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
20190754 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11106648 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
23392350 MGI
enables protein phosphatase binding IPI
IPI: 通过物理相互作用推断
16973135 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blood vessel morphogenesis IMP
IMP: 通过突变表型推断
15809310 MGI
acts upstream of or within brain morphogenesis IGI
IGI: 通过遗传相互作用推断
25100583 MGI
acts upstream of or within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IDA
IDA: 通过直接分析推断
14561752 MGI
acts upstream of or within cell adhesion IDA
IDA: 通过直接分析推断
12738802 MGI
acts upstream of or within cell migration IDA
IDA: 通过直接分析推断
14561752 MGI
involved in cell-cell adhesion IDA
IDA: 通过直接分析推断
9655503 MGI
involved in cell-cell adhesion mediated by cadherin IDA
IDA: 通过直接分析推断
24952463 MGI
involved in cell-cell junction assembly IMP
IMP: 通过突变表型推断
26750727 MGI
acts upstream of or within cerebral cortex development IGI
IGI: 通过遗传相互作用推断
25100583 MGI
involved in glial cell differentiation IDA
IDA: 通过直接分析推断
24952463 MGI
acts upstream of or within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
IDA: 通过直接分析推断
8270638 MGI
acts upstream of or within homeostasis of number of cells IGI
IGI: 通过遗传相互作用推断
25100583 MGI
acts upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules IDA
IDA: 通过直接分析推断
8270638 MGI
acts upstream of or within mesenchymal cell migration IMP
IMP: 通过突变表型推断
17507657 MGI
acts upstream of or within negative regulation of canonical Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
19075000 MGI
involved in neural crest cell development IMP
IMP: 通过突变表型推断
26750727 MGI
acts upstream of or within neuroepithelial cell differentiation IGI
IGI: 通过遗传相互作用推断
25100583 MGI
involved in neuroligin clustering involved in postsynaptic membrane assembly IMP
IMP: 通过突变表型推断
20534458 MGI
involved in neuronal stem cell population maintenance IDA
IDA: 通过直接分析推断
24952463 MGI
acts upstream of or within positive regulation of MAPK cascade IGI
IGI: 通过遗传相互作用推断
20160094 MGI
involved in positive regulation of synaptic vesicle clustering IMP
IMP: 通过突变表型推断
20534458 MGI
involved in protein localization to plasma membrane IDA
IDA: 通过直接分析推断
24046456 MGI
acts upstream of or within radial glial cell differentiation IGI
IGI: 通过遗传相互作用推断
25100583 MGI
acts upstream of or within regulation of oligodendrocyte progenitor proliferation IGI
IGI: 通过遗传相互作用推断
25100583 MGI
involved in regulation of postsynaptic density protein 95 clustering IMP
IMP: 通过突变表型推断
20534458 MGI
acts upstream of or within striated muscle cell differentiation IGI
IGI: 通过遗传相互作用推断
20160094 MGI
involved in synaptic vesicle clustering IMP
IMP: 通过突变表型推断
34702855 MGI
acts upstream of or within telencephalon development IGI
IGI: 通过遗传相互作用推断
25100583 MGI
involved in type B pancreatic cell development IMP
IMP: 通过突变表型推断
26750727 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in adherens junction IDA
IDA: 通过直接分析推断
12052883 MGI
located in apical plasma membrane IDA
IDA: 通过直接分析推断
21947081 MGI
located in apicolateral plasma membrane IDA
IDA: 通过直接分析推断
29211732 MGI
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
25512490 MGI
located in cell surface IDA
IDA: 通过直接分析推断
25232112 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
21296051 MGI
located in desmosome IDA
IDA: 通过直接分析推断
15479741 MGI
located in fascia adherens IDA
IDA: 通过直接分析推断
11732910 MGI
located in intercalated disc IDA
IDA: 通过直接分析推断
17884088 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
14657280 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
9655503 MGI
located in plasma membrane raft IDA
IDA: 通过直接分析推断
24046456 MGI
located in sarcolemma IDA
IDA: 通过直接分析推断
23392350 MGI
located in synapse IDA
IDA: 通过直接分析推断
14622577 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cadherin-2

N-cadherin

neural cadherin

重组 Cdh2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73750 N-Cadherin Protein, Mouse (HEK293) P15116 (S26-A724) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02330 CDH2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdh2 NCBI NCBI:1000
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