2. Gene
  3. Chl1 - cell adhesion molecule L1-like Gene

Chl1 - cell adhesion molecule L1-like Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CALL; LICAM2; A530023M13Rik

基因 ID: 12661 | 基因类型: protein coding

关于 Chl1

功能概要

Enables Protease binding activity. Involved in negative regulation of neuron apoptotic process. Acts upstream of or within several processes, including adult locomotory behavior; exploration behavior; and generation of neurons. Located in apical part of cell and dendrite. Is expressed in nervous system and retina. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human CHL1 (cell adhesion molecule L1 like). [provided by Alliance of Genome Resources, Apr 2022]

Chl1 基因产物(1)

mRNA Protein Name
NM_007697.2 NP_031723.2 neural cell adhesion molecule L1-like protein precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protease binding IPI
IPI: 通过物理相互作用推断
14761956 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18046458 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adult locomotory behavior IMP
IMP: 通过突变表型推断
14659567 MGI
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
12391163 MGI
acts upstream of or within cognition IMP
IMP: 通过突变表型推断
14659567 MGI
acts upstream of or within exploration behavior IMP
IMP: 通过突变表型推断
12391163 MGI
NOT acts upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules IDA
IDA: 通过直接分析推断
10103075 MGI
involved in negative regulation of neuron apoptotic process IDA
IDA: 通过直接分析推断
14761956 MGI
acts upstream of or within neuron migration IMP
IMP: 通过突变表型推断
15504324 MGI
acts upstream of or within neuron projection development IDA
IDA: 通过直接分析推断
10103075 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical part of cell IDA
IDA: 通过直接分析推断
15504324 MGI
located in dendrite IDA
IDA: 通过直接分析推断
15504324 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neural cell adhesion molecule L1-like protein

cell adhesion molecule with homology to L1CAM

chl1-like protein

close homolog of L1

重组 Chl1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75344 CHL1 Protein, Mouse (HEK293, His) XP_017176866 (A25-Q1027) ≥95%
HY-P75345 CHL1 Protein, Mouse (HEK293, hFc) XP_017176866 (A25-Q1027) ≥95%
HY-P75346 CHL1 Protein, Mouse (HEK293) XP_017176866 (A25-Q1027) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02635 CHL1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chl1 NCBI NCBI:10752
Rattus norvegicus Chl1 NCBI NCBI:89828
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