2. Gene
  3. Cntf - ciliary neurotrophic factor Gene

Cntf - ciliary neurotrophic factor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 12803 | 基因类型: protein coding

关于 Cntf

功能概要

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes, and it may be involved in reducing tissue destruction during inflammatory attacks. A read-through transcript variant composed of Zfp91 and CNTF sequences has been identified, but it is thought to be non-coding. Read-through transcription of Zfp91 and CNTF has been observed in both human and mouse. [provided by RefSeq, Aug 2008]

Cntf 基因产物(1)

mRNA Protein Name
NM_170786.2 NP_740756.1 ciliary neurotrophic factor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within muscle organ morphogenesis IGI
IGI: 通过遗传相互作用推断
15716414 MGI
acts upstream of or within negative regulation of photoreceptor cell differentiation IDA
IDA: 通过直接分析推断
15207851 MGI
acts upstream of or within neuron development IGI
IGI: 通过遗传相互作用推断
15716414 MGI
acts upstream of or within positive regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
15051883 MGI
acts upstream of or within positive regulation of tyrosine phosphorylation of STAT protein IDA
IDA: 通过直接分析推断
15207851 MGI
acts upstream of or within regulation of retinal cell programmed cell death IDA
IDA: 通过直接分析推断
11747369 MGI
acts upstream of retinal rod cell differentiation IDA
IDA: 通过直接分析推断
15207851 MGI
acts upstream of tyrosine phosphorylation of STAT protein IDA
IDA: 通过直接分析推断
15207851 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
15207851 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ciliary neurotrophic factor

重组 Cntf 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7147 CNTF Protein, Mouse P51642 (A2-M198) ≥95%
HY-P74242 CNTF Protein, Mouse (His) Q544D1 (A2-M198) ≥95%
HY-P74242AF Animal-Free CNTF Protein, Mouse (His) P51642 (M1-M198) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02923 CNTF Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cntf NCBI NCBI:1270
Rattus norvegicus Cntf NCBI NCBI:25707
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