2. Gene
  3. DUSP15 - dual specificity phosphatase 15 Gene

DUSP15 - dual specificity phosphatase 15 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：双特异性磷酸酶 15

种属: Homo sapiens

同用名: VHY; C20orf57

基因 ID: 128853 | 基因类型: protein coding

关于 DUSP15

Cytogenetic location: 20q11.21 Genomic coordinates (GRCh38): 20:31,845,593-31,870,664 (from NCBI)

This gene has 10 transcripts (splice variants), 109 orthologues and 30 paralogues. Biased expression in testis (RPKM 10.5), kidney (RPKM 3.2) and 1 other tissue.

功能概要

该基因编码的蛋白质同时具有蛋白酪氨酸磷酸酶活性和丝氨酸/苏氨酸特异性磷酸酶活性，因此被称为双特异性磷酸酶。这种蛋白质可能在少突胶质细胞的分化中起作用。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 2 月]

The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific Phosphatase activity, and therefore is known as a dual specificity Phosphatase. This protein may function in the differentiation of oligodendrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

DUSP15 基因产物(5)

mRNA Protein Name
NM_001012644.3 NP_001012662.1 dual specificity protein phosphatase 15 isoform b
NM_001320478.1 NP_001307407.1 dual specificity protein phosphatase 15 isoform c
NM_001320479.1 NP_001307408.1 dual specificity protein phosphatase 15 isoform d
NM_080611.5 NP_542178.2 dual specificity protein phosphatase 15 isoform a
NM_177991.3 NP_817130.1 dual specificity protein phosphatase 15 isoform b

DUSP15 蛋白结构

DSPc

DSPc: Dual specificity phosphatase, catalytic domain (9 - 135)

  • 0
  • 100
  • 200
  • 295 a.a.
蛋白主名 其他名称

dual specificity protein phosphatase 15

VH1-related member Y

DUSP15 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
DUSP15 Q9H1R2 NCK1 Homo sapiens P16333
Peptide Array
17474147
种属内
DUSP15 Q9H1R2 PLCG1 Homo sapiens P19174
Peptide Array
17474147
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Nanophthalmos

Nanophthalmia
Autism Spectrum Disorder

Asd

Autism Spectrum Disorders

Autistic Continuum

Pervasive Developmental Disorder

Pervasive Development Disorder

Autistic Behavior

Autistic Disorder

Autistic

Autistic Disorder Of Childhood Onset

Infantile Autism

Childhood Autism

Kanner Syndrome

Pervasive Developmental Delay Nos

Pervasive Developmental Disorder, Not Otherwise Specified
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04056 DUSP15 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus DUSP15 VGNC VGNC:50028
Canis familiaris DUSP15 VGNC VGNC:103673
Mus musculus DUSP15 MGD MGI:1934928
Felis catus DUSP15 VGNC VGNC:61663
Rattus norvegicus DUSP15 RGD RGD:1305990
Macaca mulatta DUSP15 VGNC VGNC:71848
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