2. Gene
  3. TRIM43 - tripartite motif containing 43 Gene

TRIM43 - tripartite motif containing 43 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含三方基序 43

种属: Homo sapiens

同用名: TRIM43A

基因 ID: 129868 | 基因类型: protein coding

关于 TRIM43

This gene has 1 transcript (splice variant), 93 orthologues and 80 paralogues. Low expression observed in reference dataset.

功能概要

预测可启用泛素蛋白连接酶活性。预计参与先天免疫反应；蛋白质泛素化；和基因表达的调控。预计在细胞质中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TRIM43 基因产物(1)

mRNA Protein Name
NM_138800.3 NP_620155.1 tripartite motif-containing protein 43
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TRIM43 蛋白结构

zf-C3HC4_4

zf-C3HC4_4: zinc finger of C3HC4-type, RING (15 - 55)

SPRY

SPRY: SPRY domain (335 - 443)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 446 a.a.
蛋白主名 其他名称

tripartite motif-containing protein 43

TRIM43 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TRIM43 Q96BQ3 GRB7 Homo sapiens Q14451-3
Y2H Array
32296183
种属内
TRIM43 Q96BQ3 GRB7 Homo sapiens Q14451-3
Y2H Prey Pooling
32296183
种属内
TRIM43 Q96BQ3 TGFBR2 Homo sapiens P37173
Validated Y2H
32814053
种属内
TRIM43 Q96BQ3 TGFBR2 Homo sapiens P37173
Y2H Pooling
32814053
种属内
TRIM43 Q96BQ3 TGFBR2 Homo sapiens P37173
Y2H Array
32814053
种属内
TRIM43 Q96BQ3 UBE2K Homo sapiens P61086
Validated Y2H
32814053
种属内
TRIM43 Q96BQ3 UBE2K Homo sapiens P61086
Y2H Array
32814053
种属内
TRIM43 Q96BQ3 UBE2K Homo sapiens P61086
Y2H Pooling
32814053
种属内
TRIM43 Q96BQ3 ENOX1 Homo sapiens Q8TC92
Validated Y2H
25416956
种属内
TRIM43 Q96BQ3 ENOX1 Homo sapiens Q8TC92
Y2H Prey Pooling
32296183
种属内
TRIM43 Q96BQ3 ENOX1 Homo sapiens Q8TC92
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Facioscapulohumeral Muscular Dystrophy 1

Facioscapulohumeral Muscular Dystrophy

Fshd

Landouzy-Dejerine Muscular Dystrophy

Muscular Dystrophy, Facioscapulohumeral

FSHD1

Fshd1a

Muscular Dystrophy, Facioscapulohumeral, Type 1a

Facioscapulohumeral Muscular Dystrophy Type 1a

Fsh Muscular Dystrophy

Facioscapulohumeral Muscular Dystrophy 1a

Facioscapulohumeral Atrophy

Facioscapulohumeral Myopathy

Muscular Dystrophy, Facioscapulohumeral, Type 1

Facioscapulohumeral Muscular Dystrophy Type 1

Landouzy Dejerine Muscular Dystrophy

Muscular Dystrophy, Landouzy-Dejerine

Fshmd1a

Facio-Scapulo-Humeral Dystrophy

Facioscapulohumeral Type Progressive Muscular Dystrophy

Facioscapuloperoneal Muscular Dystrophy

Facioscapulohumeral Dystrophy

Fsh Dystrophy

Landouzy-Dejerine Dystrophy

Landouzy-Dejerine Myopathy

Fmd

Facioscapulohumeral Muscular Dystrophy-1a

Muscular Dystrophy Facioscapulohumeral

Dystrophy, Muscular, Facioscapulohumeral

Dystrophy, Muscular, Facioscapulohumeral, Type 1

Landouzy-Dejerine Disease

Landouzy-Déjerine Atrophy

Facioscapulohumeral Muscle Dystrophy

Fmd - [Facioscapulohumeral Muscular Dystrophy]

Fsh - [Facioscapulohumeral Muscular Dystrophy]

Fshd - [Facioscapulohumeral Muscular Dystrophy]

Landouzy-Déjerine Dystrophy Or Facioscapulohumeral Atrophy

Landouzy-Déjérine Muscular Dystrophy
Facioscapulohumeral Muscular Dystrophy 2, Digenic

Facioscapulohumeral Muscular Dystrophy 2

FSHD2

Fshd1b

Facioscapulohumeral Muscular Dystrophy 1b

Fshd2, Digenic

Muscular Dystrophy, Facioscapulohumeral, Type 2

Muscular Dystrophy, Facioscapulohumeral, Type 1b

Fascioscapulohumeral Muscular Dystrophy 2, Digenic

Facioscapulohumeral Muscular Dystrophy Type 2

Digenic Facioscapulohumeral Muscular Dystrophy

Digenic Fshd2

Facioscapulohumeral Muscular Dystrophy Type 1b

Dystrophy, Muscular, Facioscapulohumeral, Type 2
Digenic Disease
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15047 TRIM43 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TRIM43 RGD RGD:1561074
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