2. Gene
  3. M1AP - meiosis 1 associated protein Gene

M1AP - meiosis 1 associated protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：减数分裂 1 相关蛋白

种属: Homo sapiens

同用名: D6Mm5e; SPGF48; C2orf65; SPATA37

基因 ID: 130951 | 基因类型: protein coding

关于 M1AP

Cytogenetic location: 2p13.1 Genomic coordinates (GRCh38): 2:74,557,883-74,648,330 (from NCBI)

This gene has 9 transcripts (splice variants), 174 orthologues and is associated with 1 phenotype. Biased expression in testis (RPKM 3.3), bone marrow (RPKM 2.4) and 8 other tissues.

功能概要

该基因编码的蛋白质可能在减数分裂的进程中发挥作用。小鼠中的一种相似蛋白质在两种性别的配子发生中都起作用。交替剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2013 年 7 月]

This gene encodes a protein that is likely to function in progression of meiosis. A similar protein in mouse plays a role in gametogenesis in both sexes. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

M1AP 基因产物(4)

mRNA Protein Name
NM_001281295.2 NP_001268224.1 meiosis 1 arrest protein isoform 2
NM_001281296.2 NP_001268225.1 meiosis 1 arrest protein isoform 3
NM_001321739.2 NP_001308668.1 meiosis 1 arrest protein isoform 1
NM_138804.5 NP_620159.2 meiosis 1 arrest protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in spermatogenesis IMP
IMP: 通过突变表型推断
32673564 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

meiosis 1 arrest protein

meiosis 1 arresting protein

M1AP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra M1AP Q8TC57 DES Homo sapiens P17661
Y2H Prey Pooling
32296183
Intra M1AP Q8TC57 DES Homo sapiens P17661
Y2H Array
32296183
Intra M1AP Q8TC57 SIAH1 Homo sapiens Q8IUQ4-2
Y2H Prey Pooling
32296183
Intra M1AP Q8TC57 SIAH1 Homo sapiens Q8IUQ4-2
Y2H Array
32296183
Intra M1AP Q8TC57 POLR3GL Homo sapiens Q9BT43
Validated Y2H
32296183
Intra M1AP Q8TC57 TRIP13 Homo sapiens Q15645
Y2H Array
25416956
Intra M1AP Q8TC57 TRIP13 Homo sapiens Q15645
Y2H Prey Pooling
25416956
Intra M1AP Q8TC57 TRIP13 Homo sapiens Q15645
Validated Y2H
25416956
Intra M1AP Q8TC57 PLEKHA2 Homo sapiens Q9HB19
Y2H Prey Pooling
32296183
Intra M1AP Q8TC57 PLEKHA2 Homo sapiens Q9HB19
Validated Y2H
32296183
Intra M1AP Q8TC57 PLEKHA2 Homo sapiens Q9HB19
Y2H Array
32296183
Intra M1AP Q8TC57 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra M1AP Q8TC57 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra M1AP Q8TC57 BAHD1 Homo sapiens Q8TBE0
Y2H Prey Pooling
32296183
Intra M1AP Q8TC57 BAHD1 Homo sapiens Q8TBE0
Y2H Array
32296183
Intra M1AP Q8TC57 CRX Homo sapiens O43186
Y2H Prey Pooling
32296183
Intra M1AP Q8TC57 CRX Homo sapiens O43186
Y2H Array
32296183
Intra M1AP Q8TC57 M1AP Homo sapiens Q8TC57
Validated Y2H
32296183
Intra M1AP Q8TC57 OTX2 Homo sapiens P32243-2
Y2H Prey Pooling
32296183
Intra M1AP Q8TC57 M1AP Homo sapiens Q8TC57
Y2H Prey Pooling
32296183
Intra M1AP Q8TC57 OTX2 Homo sapiens P32243-2
Y2H Array
32296183
Intra M1AP Q8TC57 M1AP Homo sapiens Q8TC57
Y2H Array
25416956
Intra M1AP Q8TC57 M1AP Homo sapiens Q8TC57
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Spermatogenic Failure 48

SPGF48
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
Infertility
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07936 M1AP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus M1AP MGD MGI:1315200
Canis familiaris M1AP VGNC VGNC:42907
Bos taurus M1AP VGNC VGNC:31124
Rattus norvegicus M1AP RGD RGD:1563842
Felis catus M1AP VGNC VGNC:63355
Macaca mulatta M1AP VGNC VGNC:74354
Others M1AP NCBI
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