2. Gene
  3. TPRA1 - transmembrane protein adipocyte associated 1 Gene

TPRA1 - transmembrane protein adipocyte associated 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：跨膜蛋白脂肪细胞相关 1

种属: Homo sapiens

同用名: GPR175; TPRA40; TMEM227

基因 ID: 131601 | 基因类型: protein coding

关于 TPRA1

Cytogenetic location: 3q21.3 Genomic coordinates (GRCh38): 3:127,571,232-127,598,231 (from NCBI)

This gene has 12 transcripts (splice variants) and 198 orthologues. Ubiquitous expression in placenta (RPKM 7.3), endometrium (RPKM 6.7) and 25 other tissues.

功能概要

预计可启用 G 蛋白偶联受体活性。预测参与 G 蛋白偶联受体信号通路。预计在胚胎卵裂的上游或胚胎卵裂内起作用，并对有丝分裂细胞周期相变进行负调节。预计是膜的组成部分。预计在质膜上有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within embryonic cleavage and negative regulation of mitotic cell cycle phase transition. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TPRA1 基因产物(9)

mRNA Protein Name
NM_001136053.4 NP_001129525.1 transmembrane protein adipocyte-associated 1 isoform 1
NM_001142646.4 NP_001136118.1 transmembrane protein adipocyte-associated 1 isoform 2
NM_001353001.2 NP_001339930.1 transmembrane protein adipocyte-associated 1 isoform 1
NM_001353002.2 NP_001339931.1 transmembrane protein adipocyte-associated 1 isoform 1
NM_001353003.2 NP_001339932.1 transmembrane protein adipocyte-associated 1 isoform 1
NM_001353004.2 NP_001339933.1 transmembrane protein adipocyte-associated 1 isoform 1
NM_001353005.2 NP_001339934.1 transmembrane protein adipocyte-associated 1 isoform 1
NM_001353006.2 NP_001339935.1 transmembrane protein adipocyte-associated 1 isoform 3
NM_001353007.2 NP_001339936.1 transmembrane protein adipocyte-associated 1 isoform 4
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25464930 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TPRA1 蛋白结构

Tmemb_40

Tmemb_40: Predicted membrane protein (35 - 312)

  • 0
  • 100
  • 200
  • 300
  • 373 a.a.
蛋白主名 其他名称

transmembrane protein adipocyte-associated 1

G protein-coupled receptor 175

TPRA1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TPRA1 Q86W33 NLGN3 Homo sapiens Q9NZ94-2
Anti Tag CoIP
25464930
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Fox-Fordyce Disease

Fox Fordyce Disease

Apocrine Miliaria

Fox-Fordyce Syndrome

Miliaria, Apocrine
Dyschromatosis Universalis Hereditaria

Duh
Atrophic Rhinitis

Rhinitis, Atrophic

Ozena

Rhinitis Sicca

Dry Rhinitis

Ozaena
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14947 TPRA1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta TPRA1 VGNC VGNC:79848
Mus musculus TPRA1 MGD MGI:1345190
Felis catus TPRA1 VGNC VGNC:66484
Canis familiaris TPRA1 VGNC VGNC:47752
Rattus norvegicus TPRA1 RGD RGD:620858
Bos taurus TPRA1 VGNC VGNC:54506
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