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  2. NUDCD2 - NudC domain containing 2 Gene

NUDCD2 - NudC domain containing 2 Gene

中文名称:含 NudC 域 2

种属: Homo sapiens

同用名: NudCL2

基因 ID: 134492 | 基因类型: protein coding

关于 NUDCD2

This gene has 4 transcripts (splice variants), 199 orthologues and 2 paralogues. Ubiquitous expression in fat (RPKM 16.1), prostate (RPKM 14.4) and 25 other tissues.

功能概要

预计会启用未折叠的蛋白质结合活性。预测参与蛋白质折叠。位于胞质溶胶中;细胞间桥;和有丝分裂纺锤体。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Located in cytosol; intercellular bridge; and mitotic spindle. [provided by Alliance of Genome Resources, Apr 2022]

NUDCD2 基因产物(2)

mRNA Protein Name
NM_001329991.2 NP_001316920.1 nudC domain-containing protein 2 isoform 2
NM_145266.6 NP_660309.1 nudC domain-containing protein 2 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20133715 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

NUDCD2 蛋白结构

CS

CS: CS domain (19 - 91)

  • 0
  • 100
  • 157 a.a.
蛋白主名 其他名称

nudC domain-containing protein 2

NudC-like protein 2

NUDCD2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra NUDCD2 Q8WVJ2 DDX3Y Homo sapiens O15523
Anti Tag CoIP
33961781
Intra NUDCD2 Q8WVJ2 DDX3Y Homo sapiens O15523
Anti Tag CoIP
28514442
Intra NUDCD2 Q8WVJ2 HSP90AA1 Homo sapiens P07900
Pull Down
20133715
Intra NUDCD2 Q8WVJ2 HSP90AA1 Homo sapiens P07900
Anti Tag CoIP
20133715
Intra NUDCD2 Q8WVJ2 HSP90AA1 Homo sapiens P07900
Anti Bait CoIP
20133715
Intra NUDCD2 Q8WVJ2 PRMT5 Homo sapiens O14744
Anti Tag CoIP
23455924
Intra NUDCD2 Q8WVJ2 PRMT5 Homo sapiens O14744
Y2H
23455924
Intra NUDCD2 Q8WVJ2 FBXO24 Homo sapiens O75426
Lumier
25036637
Intra NUDCD2 Q8WVJ2 PAFAH1B1 Homo sapiens P43034
Anti Bait CoIP
20133715
Intra NUDCD2 Q8WVJ2 PAFAH1B1 Homo sapiens P43034
Pull Down
20133715
Intra NUDCD2 Q8WVJ2 PAFAH1B1 Homo sapiens P43034
Anti Tag CoIP
20133715
Intra NUDCD2 Q8WVJ2 OPTN Homo sapiens Q96CV9
Y2H Pooling
32814053
Intra NUDCD2 Q8WVJ2 OPTN Homo sapiens Q96CV9
Validated Y2H
32814053
Intra NUDCD2 Q8WVJ2 OPTN Homo sapiens Q96CV9
Y2H Array
32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Bardet-Biedl Syndrome 12

BBS12

Bardet-Biedl Syndrome

Bbs

Bardet-Biedl Syndrome, Type 12

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus NUDCD2 RGD RGD:1307203
Canis familiaris NUDCD2 VGNC VGNC:44023
Felis catus NUDCD2 VGNC VGNC:102273
Bos taurus NUDCD2 VGNC VGNC:32323
Mus musculus NUDCD2 MGD MGI:1277103