F2rl1 - coagulation factor II (thrombin) receptor-like 1 Gene

中文名称：凝血因子 II (凝血酶) 受体样 1

种属: Mus musculus

同用名: Par2; PAR-2; Gpcr11

关于 F2rl1

功能概要

该基因编码的蛋白可启动 G 蛋白偶联受体活性； G蛋白α-亚基结合活性；和 G 蛋白 β-亚基结合活性。参与多个过程，包括成熟的常规树突状细胞分化；细胞因子产生的正调节；和细胞内信号转导的正调控。位于伪讲台。以多种结构表达，包括消化系统；中枢神经系统;泌尿生殖系统；感觉器官；和皮肤。与哮喘有关的该基因的人类直系同源物；慢性阻塞性肺疾病;和呼吸道过敏。与人 F2RL1（F2R 样胰蛋白酶受体 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables G protein-coupled receptor activity; G-protein alpha-subunit binding activity; and G-protein beta-subunit binding activity. Involved in several processes, including mature conventional dendritic cell differentiation; positive regulation of cytokine production; and positive regulation of intracellular signal transduction. Located in pseudopodium. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skin. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and respiratory allergy. Orthologous to human F2RL1 (F2R like trypsin receptor 1). [provided by Alliance of Genome Resources, Apr 2022]