2. Gene
  3. Gad2 - glutamic acid decarboxylase 2 Gene

Gad2 - glutamic acid decarboxylase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: GAD65; Gad-2; GAD(65); 6330404F12Rik

基因 ID: 14417 | 基因类型: protein coding

关于 Gad2

功能概要

Predicted to enable glutamate binding activity; glutamate decarboxylase activity; and pyridoxal phosphate binding activity. Predicted to be involved in glutamate decarboxylation to succinate. Predicted to act upstream of or within neurotransmitter biosynthetic process. Located in axon; cytoplasm; and synapse. Is expressed in several structures, including genitourinary system; gut; heart; nervous system; and sensory organ. Used to study epilepsy and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in gestational diabetes; schizophrenia; and type 1 diabetes mellitus. Orthologous to human GAD2 (glutamate decarboxylase 2). [provided by Alliance of Genome Resources, Apr 2022]

Gad2 基因产物(1)

mRNA Protein Name
NM_008078.2 NP_032104.2 glutamate decarboxylase 2
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
15479642 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
23500099 MGI
located in synapse IDA
IDA: 通过直接分析推断
15479642 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

glutamate decarboxylase 2

65 kDa glutamic acid decarboxylase

GAD-65

重组 Gad2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75177 GAD2/GAD65 Protein, Mouse (sf9, His-GST) Q548L4 (M1-L585) ≥95%
HY-P75178 GAD2/GAD65 Protein, Mouse (sf9) Q548L4 (N-G&P, M1-L585) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05228 GAD2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gad2 NCBI NCBI:2572
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